Chapter 5: Nutrition in Humans Flashcards

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1
Q

What is physical digestion?

A

-Mechanical break-up of food into smaller pieces
-No enzymes involved
-Increases surface area to volume ratio of food particles for higher rate of digestion

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2
Q

What is chemical digestion?

A

-Break-down of large molecules in food into small soluble molecules that can be absorbed into body cells
-Hydrolytic reactions catalysed by enzymes

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3
Q

Describe digestion in the mouth.
(Physical & Chemical)

A

Physical:
-Teeth break down large pieces of food into smaller pieces

Chemical:
-Salivary glands secrete saliva (containing salivary amylase & mucin) into the mouth.
-Salivary amylase catalyses digestion of starch to maltose
-Mucin softens food

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4
Q

Describe peristalsis.

A

-The rhythmic, wave-like muscular contraction in the wall along the alimentary canal.
-Wall of alimentary canal constricts to push food forward (circ musc contract, long musc relax)
-Wall of alimentary canal dilates to allow food to enter (circ musc relax, long musc contract)

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5
Q

Describe digestion in the stomach.
(Physical & Chemical + OTHER)

A

Physical:
-Peristalsis in stomach walls mixes food w/ gastric juice. (churning)

Chemical:
-Pepsin catalyses breakdown of proteins into polypeptides

OTHER:
-Hydrochloric acid denatures salivary amylase, converts inactive pepsinogen into pepsin, kills harmful organisms in food
-Mucus protects stomach wall from being digested by pepsin, lubricates food for easy movement in stomach

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6
Q

What are the 3 parts of the small intestine?

A

Duodenum
Jejunum
Ileum

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7
Q

Describe digestion in the small intestine.
(Physical & Chemical + OTHER)

A

Physical:
-Bile (produced in liver, stored in gallbladder) helps speed up fat digestion by emulsifying large fat globules into smaller fat droplets.
-Peristalsis

Chemical:
1. Carbohydrate digestion:
Starch (pancreatic amylase) -> maltose (intestinal maltase) -> glucose
2. Protein digestion:
Protein (pancreatic trypsin)-> polypeptide (intestinal peptidase)-> amino acid
3. Fat digestion (pancreatic & intestinal lipase)-> fatty acids+glycerol
4. Sucrose (intestinal sucrase)-> glucose+fructose
5. Lactose (intestinal lactase)-> glucose+galactose

OTHER:
-Pancreatic juice, intestinal juice & bile->alkaline, neutralise acidic chyme

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8
Q

Large intestine consists of?

A

Colon
Rectum

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9
Q

What is the main function of the colon?

A

Absorb water and mineral salts from undigested food material.

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10
Q

What is the main function of the rectum?

A

Temporarily stores faeces before it expels through the anus.

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11
Q

What are the factors that increase the rate of absorption?

A
  1. Large surface area
  2. Thin separating material
  3. Steep concentration gradient
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12
Q

How is the small intestine adapted for its function?

A

1. Large surface area
-Inner surface of ileum is folded extensively, has numerous villi to increase surface area to volume ratio for increased rate of absorption of nutrients
-Epithelial cells of villi have many microvilli, further increase ~~~
-Long length of small intestine, more time for absorption to take place

2. Thin separating material
-Wall of the epithelium is only one-cell thick, to provide shorter diffusion distance.

3. Steep concentration gradient
-Dense network of blood capillaries, to help carry absorbed glucose and amino acids away quickly to maintain steep conc gradient
-Lacteal in each villus to transport fats away from intestine

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13
Q

How are glucose and amino acids absorbed into the bloodstream?

A

-Diffuse into the blood capillaries of the villi
-By active transport (when lower conc in lumen than villi)

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14
Q

How are fats absorbed into the bloodstream?

A

-Fatty acids & glycerol diffuse into epithelium, then combine to form minute fat globules which enter the lacteals

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15
Q

How are glucose and amino acids transported and assimilated?

A

Transported from small intestine to liver by hepatic portal vein

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16
Q

How are fats transported and assimilated?

A

-Lymphatic capillaries->larger lymphatic vessels
-Larger lymphatic vessels discharge fats into bloodstream, blood carries fats to all parts of body, esp liver

17
Q

What are the (5) functions of the liver?

A
  1. Regulation of blood glucose concentration
  2. Production of bile
  3. Deamination of amino acids
  4. Breakdown of hormones
  5. Detoxification
18
Q

Describe the regulation of blood glucose concentration in the liver.

A

Blood glucose conc is kept constant

-When glucose lvl in blood is too HIGH:
Pancreas [Islets of Langerhans] secrete insulin, stimulates liver cells to convert
excess GLUCOSE to GLYCOGEN to reduce blood glucose conc

-When glucose lvl in blood is too LOW:
Pancreas [Islets of Langerhans] secrete glucagon, stimulates liver cells to convert GLYCOGEN to GLUCOSE to increase blood glucose conc

19
Q

Describe the deamination of amino acids in the liver.

A

-Amino group is removed and converted to urea
-Urea is removed from body in urine
-Carbon residues of aa are converted to glucose in liver
-Excess glucose (from above) is converted to glycogen

20
Q

Describe detoxification in the liver.

A

Liver cells contain an enzyme call alcohol dehydrogenase, which converts alcohol (harmful) into acetaldehyde (harmless)

21
Q

What are the harmful effects of alcohol consumption on the digestive system?

A

-Stimulates acid secretion in stomach, excess stomach acid->increased rick of gastric ulcers
-[Prolonged abuse] Liver cirrhosis, where healthy liver cells are damaged and replaced w/ fibrous tissue, impairing liver functions
-May cause hemmorrhage in liver->liver faiure->death

22
Q

What are the harmful effects of alcohol consumption on the nervous system?

A

-Depressant, slows down some brain functions
-Reduced self-control
-Increased reaction times, blurred vision, poor muscular coordination, impaired judgements
-[Long-term] Wet brain & brain shrinkage

23
Q

What are the social implications of alcohol abuse?

A

-Addiction as body becomes dependant on alcohol
-Social problems, e.g. neglect of work & family, violent behaviour, tendency to commit crimes etc.