Chapter 5: Membrane Structure and Function Flashcards
What is the plasma membrane?
the barrier of all living cells and exhibits selective permability due to the fact that it allows some substances to move easily across while keeping other out.
What are aquaporins?
one type of membrane protein that allows for water to pass through a membrane (many more than would pass through on their own)
What are lipids?
and proteins are the main ingredients of membranes, carbohydrates also make up part of the membrane
WHat does amphipathic mean?
hydrophobic and hydrophillic
What does the fluid mosaic model explain?
the liquid nature of the membrane with proteins embedded in it
How thick is the plasma membrane?
to layers thick, hence its name
What is the membrane also known as?
a mosaic due to its variety and number of components
What is a glycoprotein’s function?
cell recognition
What are oligosaccharides’ function?
tags for membrane, markers
What are glycolipids’ used for?
cell recognition
What is the extracellular matrix’s function?
hold some peripheral proteins- support
What is the cytoskeleton’s function?
give sturcutre to the cell, helps to facilitate movement
What is the integral proteins’ function?
transport molecules into & out of cells
What is peripheral proteins’ functions?
act as enzyme to carry out chem RXNs
What is cholesterol’s function?
maintains liquid nature of the cell membrane
Is it possible for phospholipids to move easily within the cell membrane? Explain.
Phospholipids are held together (to other phospholipids) primarily by hydrophobic interactions, wichh are much weaker than covalent bonds (they move through the membrane like party goers moivng through a room)
Explain what occured with Larry Frye and Michael Edidin’s experiment and what it showed.
THey labeled the proteins of a mouse and human cell and then saw how they mixed (moved) across the membrane over one hour.
WHat would you conclude about the proteins if, in a similar experiment, the proteins did not move at all?
You would assume that they are connected to the cytoskeleton of the cell
What are the reasosn that a membrane remains fluid at low temperatures?
Unsaturated fatty acids in plant cells, and cholesterol molecules in animal cells
What do fish that live in cold enviroments have?
a high proportion of unsaturated fatty acids in their phospholipids allowing their membranes to remain fluid at low tems
Plants that are able to tolerate extreme cold will have:
higher percentage of unsaturated phospholipids in the winter, and low percentage of unsaturated phospholipids in the summer
What are integral proteins?
proteins that extend all the way or partially through the cell membrane (the majority are transmembrane proteints)
What are peripheral proteins?
proteins that lie completely outside the bilayre
What are functions of the membrane protein?
transport, enzymatic activity, signal transduction, cell to cell recognition, intercellular joining (tight junction, gap junction), attach to cytoskeleton and ECM
What do glycoproteins and glycolipids help to identify?
cells, e.x. cell recognition, sorting of cells into embryonic tissues, identifying foriegn cells
How are transmemrane glycoproteins oriented in the ER?
carb portion facing into the ER for modification