chapter 5: cell recognition and the immune system Flashcards

1
Q

What is an infection

A

an interaction between the pathogen and the bodies defence mechanisms

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2
Q

types of lymphocytes response

A
  1. cell mediated response involving T lymphocytes
  2. humoral response involving b lymphocytes
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3
Q

non specific response

A

immediate and same for all pathogens

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4
Q

specific response

A

slower and specific to each pathogen

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5
Q

non specific examples

A
  1. physical barriers
  2. phagocytes
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6
Q

specific response examples

A
  1. cell mediated response (t lymphocytes)
  2. humoral response (b lymphocytes )
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7
Q

how do lymphocytes recognise cell belonging to the body (fetus)

A
  1. in the fetus lymphocytes are colliding with other cells
    2.infection in the fetus is rare
  2. lymphocytes will only collide with the body own cells
    4.lymphocytes with the complementary receptors to the bodies cell will be killed or suppressed
  3. only lymphocytes that fight foreign material are left
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8
Q

how lymphocytes recognise cells belonging to the body (adult)

A
  1. lymphocytes produced in the bone marrow initially only encounter self antigens
  2. lymphocytes that show an immune response to the self antigens will undergo cell death (apoptosis)
  3. only lymphocytes that respond to foreign material are left
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9
Q

types of white blood cells

A
  1. phagocytes
  2. lymphocytes
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10
Q

phagocytes

A

ingest and destroy the pathogen by phagocytosis

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11
Q

lymphocytes

A

involved in immune response

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12
Q

phagocytes

A

large particles are engulfed by cells in the vesicles formed form the cell surface membrane

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13
Q

phagocytes (role)

A

carry out phagocytosis

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14
Q

phagocytosis process

A

1.chemical products of pathogens act as attractants for the phagocytes
2. phagocytes have receptors on their cell surface membrane that recognise and attach to chemicals on the surface of the pathogen
3. engulf the pathogen to form a vesicle (phagosome)
lysosomes fuse with the vesicle
lysosomes destroy bacteria by hydrolysis of cell wall

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15
Q

the initial response of the body

A

non- specific

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16
Q

immunity

A

the ability of organisms to resist infections by protecting against disease- causing microorganisms. involves the recognition of antigens

17
Q

what is an antigen

A

any part of an organism that is recognised as non self. stimulates an innume resposne

18
Q

the presence of a antigen…

A

triggers the production of an antibody as part of the bodies defence system

19
Q

t lyphocyests can distuinsgust invader cells form normal cells v]becaue

A
  1. phagocytes present a pathogens antigen on its surface
  2. body cells invaded by viruses presented its antigen on its surface
  3. transplanted cells from the same species have different antigens
  4. cancer cells have different antigens
20
Q

cells that present foreign antigens on their surface

A

antigen presenting cells