Chapter 5: Biopharmaceutical and Pharmacokinetic Considerations Flashcards
result from the entrance of the drug into the circulatory system and transport to the cellular site of its action
systemic effects
oral route of administration: systemic effect or local effect
systemic effect
most natural, uncomplicated, convenient and safe means of administering drugs
oral route
disadvantages of oral route
slow drug response,
chance of irregular absorption of drugs,
destruction of certain drugs by the acid reaction of the stomach
rectal route of administration: systemic effect or local effect
both
solid bodies of various weights and shapes intended for introduction into a body orifice
suppository
route preferred for drugs destroyed or inactivated by the environments of the stomach and intestines
rectal route
route preferred when the patient is unconscious or incapable of swallowing
rectal route
disadvantages of rectal route of administration
incovenient,
offensive
parenteral route of administration: systemic effect or local effect
systemic effect
three primary routes of parenteral administration
subcutaneous,
intramuscular,
intravenous
route preferred for drugs destroyed or inactivated in the git or too poorly absorbed to provide satisfactory response
parenteral route
route preferred when rapid absorption is essential
parenteral route
route preferred in treating patients who are uncooperative, unconscious, or otherwise unable to accept oral medication
parenteral route
disadvantage of parenteral route administration
no retreat