Chapter 5: Anxiety, OCD, Trauma, Stress-related disorders Flashcards
Anxiety
- an individuals emotional and physical fear response to a perceived threat.
Pathologic anxiety
when symptoms are excessive, irrational, out of proportion to the trigger, or without an identifiable trigger.
Maladaptive anxiety
persists longer and feels more intense than transient, situational anxiety
criteria for most anxiety disorders
involve symptoms that cause clinically significant distress or impairment in social and/or occupational functioning
can only dx if NOT due to a substance, med, or medical condition
MOST COMMON FORM OF PSYCHOPATHOLOGY
Women 2:1 men
neurotransmitters implicated in anxiety
Norepinephrine
Serotonin
GABA
Treatment of anxiety
consider psychotherapy for milder
combo treatment with pharm for moderate to severe
Signs and symptoms of anxiety
Constitutional: fatigue, diaphoresis, shivering
Cardiac: Chest pain, palpitations, tachycardia, hypertension
Pulmonary: SOB, hyperventilation
Nero/ MSK: Vertigo, light-headedness, paresthesias, tremors, insomnia, muscle tension
GI: ab discomfort, anorexia, nausea, emesis, diarrhea, constipation
Medications and substances that cause anxiety
Alcohol- intox or withdrawal Sedatives, hypnotics or anxiolitics- withdrawal cannabis- intoxication hallucinogens- intoxication stimulants- intoxication OR withdrawal caffeine- intoxication tobacco- intoxication or withdrawal opioids- withdrawal
medical conditions that cause anxiety
neurologic- epilepsy, migraines, brain tumors, MS, huntingtons
endocrine: hyperthyroid, thyrotoxicosis, hypoglycemia, pheochromocytoma, carcinoid syndrome
metabolic: vitamin B12 deficiency, electrolyte abnormalities, porphyria
Respiratory- asthma, COPD, hypoxia, PE, pneumonia, pneumothorax
CV- CHF, angina, arrhythmia, MI
Pharmacotherapy for anxiety
First line: SSRIs, SNRIs
Benzos (enhance GABA at GABA-A receptor)- quick but addictive
Buspirone- 5HT partial agonist- minimal efficacy. (augment with this)
Beta blockers - panic attacks, performance anxiety
TCAs and MAO inhibitors- if first-line agents not effective. Side-effects–> less tolerable.
Psychotherapy for anxiety
Cognitive behavioral therapy- examines relationship between anxiety-driven cognitions (thoughts), emotions, and behavior
Psychodynamic psychotherapy- facilitates understanding and insight into the development of anxiety and ultimately increases anxiety tolerance
some tips re: benzodiazepines
Benzos to Bridge until others kick in
don’t use in those with substance abuse
if comorbid depressive disorder, can worsen depression
late-onset anxiety symptoms, no prior or fam psych history?
think other medical condition or a substance
using drugs for anxiety
achieve symptomatic relief and continue treatment for at least 6 months before attempting to titrate off meds
Panic attacks
fear response- abrupt surge of intense anxiety. triggered or spontaneous.
peak within minutes, resolve within half an hour. Anxiety may continue for hours; pts may confuse this for a prolonged attack.
mnemonic: symtoms of panic attacks
Da PANICS
Dizziness, disconnectedness, derealization, depersonalization
Palpitations, paresthesias Abdominal distress Numbness, Nausea Intense fear of dying, losing control or "going crazy" Chills, Chest pain Sweatin, Shaking, SOB
risk factor for panic attacks:
smoking
PT presents with panic attack. What to rule out?
med conditions such as heart attack, thyrotoxicosis, thromboembolism
panic attacks increase risk of
suicidality
Panic disorder
spontneous** recurrent panic attacks. (no clear trigger)
can be followed by continuous worry about having more attacks (>1 month by DSM-5)
relapses common with discontinuation of medical therapy
Up to 65% have comorbid major depression
RX for panic disorder
SSRIs (sertraline, citalopram, esitalopram)
Can switch to TCAs (clomipramine, imipramine)
Can use benzos as schedule or PRN, esp. until other meds reach full efficacy
Agorophobia
intense fear of being in public places where escape or obtaining help may be difficult.
often with panic disorder
usually chronic. Very genetic.
DSM criteria: intense fear about > 2 situations
–> out of proportion to potential danger (even if they have something embarassing like IBS making it difficult to be in public)
sig social or occupational dysfunction
symptoms > 6 months
not better explained by another mental disorder
Treat with CBT and SSRIs
specific phobias/ social anxiety disorder
a phobia is an irrational fear that –> endurance of anxity and/ or avoidance of feared object/ situation.
Social anxiety disorder- fear or scrutiny by others/ fear of acting in a humiliating or embarrassing way.
PHOBIAS- most common psych d/o in women; > 10%
treatment of specific phobia
CBT
Treatment of social anxiety disorder
First line: CBT
SSRIs for debilitating symptoms
Benzos
Beta Blockers (performance anxiety/ public speaking)
Selective mutism
rare
failure to speak in specific situations at least one month, despite ability to comprehend and use language.
onset typically during childhood
most- anxiety, esp. social anxiety
may be silent or whisper.
may use nonverbal commo; writing or gesturing.
Pts with blood injury injection phobia may experience
bradycardia and hypotension–> vasovagal fainting
Dx and DSM-5 criteria for selective mutism
consistent failure to speak in select situations (e.g. school)
not due to language difficlaty or communication disorder
significant impairment in academic, occupational or social functioning
> 1 month