Chapter 5 Flashcards

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1
Q

What are the two parts of the cardiovascular system? Briefly, what are their functions?

A

a) heart, which pumps blood, and
b) blood vessels through which blood flows.

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2
Q

What is the purpose of circulation? What is the function of blood? Where is blood purified or
cleared of its wastes? At what sites does blood gain nutrients? What system collects and returns excess tissue fluid to the general circulation?

A

The purpose of circulation is to service the cells.

Blood brings oxygen and nutrients that cells need and removes their waste products.

Blood is purified of its wastes at the kidneys, liver, and lungs.

Blood gains nutrients at the lungs and intestines.

The lymphatic system collects excess tissue fluid and returns it to the cardiovascular system.

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3
Q

Name and describe the three types of blood vessels. What are their functions? How are they structurally different?

A

The three types of blood vessels are arteries, capillaries, and veins.

The Arteries: From the Heart
Arteries and arterioles always take blood away from the heart.

The arterial wall has three layers:
a) Endothelium = thin inner layer
b) Smooth muscle and elastic tissue = thick middle layer to give support under pressure and expand and spring back to absorb pressure
c) Connective tissue = outer layer for support

The constriction or dilation of arterioles controls blood pressure.

The Capillaries: Exchange
Arterioles branch into capillaries. The capillaries have walls that are only one cell thick and allow exchange of substances with tissue fluid.
Not all capillary beds are open at the same time. For example, after eating, the capillaries supplying the digestive tract are open while most capillaries serving the muscles are closed.

Contraction of a precapillary sphincter muscle closes off the bed, and then blood flows through an arteriovenous shunt, bypassing the capillary bed, going directly into a venule.

The Veins: To the Heart
Venules drain into veins that return blood to the heart.

Veins have much less smooth muscle and connective tissue than arteries.

Veins often have valves that prevent the backward flow of blood due to gravity when closed.

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4
Q

The heart is a double pump. What does this mean?

A

The heart is made up of myocardium, or cardiac muscle tissue, lying inside a fibrous pericardium.

In the heart, the right and left atria empty into the right and left ventricles, respectively.

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5
Q

Describe the structure of the heart regarding its chambers and valves. What kind of muscle is found in the heart? What is the pericardium? What are chordae tendineae? What is the function of the intercalated disks?

A

Atrioventricular valves occur between the atria and ventricles, and semilunar valves occur between the ventricles and the attached arteries.

Chordae tendineae strengthen atrioventricular valves.

Intercalated disks contain gap junctions and desmosomes, which join neighboring fibers together and make sure that cardiac fibers contract simultaneously

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6
Q

What is the function of the coronary arteries? What happens if they get clogged with cholesterol?

A

The myocardium receives oxygen and nutrients from the coronary arteries. If these arteries get clogged with cholesterol, it can lead to myocardial infarction (heart attack).

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7
Q

Trace the pathway of blood through the heart beginning with the superior and inferior vena cavae and ending with the aorta

A

1) superior and inferior vena cava,
2) right atrium,
3) right atrioventricular valve (tricuspid valve),
4) right ventricle,
5) pulmonary semilunar valve,
6) pulmonary arteries,
7) lungs,
8) pulmonary veins,
9) left atrium,
10) left atrioventricular valve (bicuspid valve),
11) left ventricle,
12) aortic semilunar valve,
13) aorta.

Oxygen-poor blood never mixes with oxygen-rich blood.

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8
Q

Define cardiac cycle. What is systole? What is diastole? What accounts for the “lub-dub” sounds when the heart beats?

A

Each heartbeat is called a cardiac cycle.
Systole = contraction phase of heartbeat
Diastole = relaxation phase of heartbeat
The heart sounds, “lub-dub,” are due to the closing of the atrioventricular valves, followed by the closing of the semilunar valves.

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9
Q

What are the functions of the following structures related to the electrical activity of the heart? sinoatrial (SA) node, atrioventricular (AV) node, atrioventricular bundle, Purkinje fibers

A

The sinoatrial (SA) node (pacemaker) initiates the beat and causes the atria to contract. The SA node is located in the upper dorsal wall of the right atrium.

The atrioventricular (AV) node conveys the stimulus and initiates contraction of the ventricles. It is located at the base of the right atrium near the septum.

The signal for the ventricles to contract travels from the AV node through the atrioventricular bundle to the smaller Purkinje fibers.

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10
Q

What role does the medulla oblongata play in control of the heartbeat? What hormones are released from the adrenal medulla to stimulate the heart?

A

A cardiac control center in the medulla oblongata regulates the heartbeat by way of the parasympathetic (slows heart rate) and the sympathetic (increases heart rate) systems.

Hormones (epinephrine and norepinephrine) of the adrenal medulla also stimulate the heart.

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11
Q

What is an electrocardiogram? What part of the cardiac cycle do the P wave, the QRS complex, and the T wave represent?

A

An electrocardiogram (ECG) is a recording of the electrical changes that occur in the myocardium during a cardiac cycle.

The P wave signals the atria are about to contract;
the QRS complex signals the ventricles are about to contract, and recovery of the ventricles produces the T wave.
The ECG can also detect various types of abnormalities, including ventricular fibrillation.

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12
Q

In what blood vessel is blood pressure the highest? In what blood vessels is blood pressure the lowest?

A

When the left ventricle contracts, a surge of blood flows through the arteries. Blood pressure is highest in the aorta and lowest in the superior and inferior vena cavae.

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13
Q

Define pulse. What causes a pulse?

A

The surge of blood entering the arteries following a heartbeat causes their elastic walls to stretch and then recoil. This is felt as a pulse. The pulse rate of the radial or carotid artery indicates the heart rate.

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14
Q

Define blood pressure. What is a sphygmomanometer? Define systolic pressure and diastolic pressure. Define hypertension and hypotension.

A

Blood pressure is the pressure of blood against the wall of a blood vessel. It is usually measured in the brachial artery of the arm with a sphygmomanometer. The higher number is the systolic pressure, and the lower number is the diastolic pressure. Normal blood pressure is 120/80. High blood pressure is called hypertension, and low blood pressure hypotension.

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15
Q

What is the advantage of blood moving through capillaries slowly?

A

Blood moves slowly in capillaries because there are more capillaries than arterioles. This slow pace allows time for exchanges between capillary blood and tissue cells.

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16
Q

What are some factors involved in the return of blood to the heart through veins? What is the importance of valves in veins?

A

Venous return is dependent upon skeletal muscle contraction, the presence of valves in veins, and respiratory movements. Once blood has moved past a valve, the valve closes, preventing backward return.

17
Q

Describe the pulmonary circuit in the cardiovascular pathway.

A

In the pulmonary circuit, pulmonary arteries take blood from the right ventricle to the lungs, carbon dioxide is given off and oxygen is picked up, and pulmonary veins return the blood to the left atrium. Pulmonary arteries carry oxygen-poor blood, while pulmonary veins carry oxygen-rich blood.

18
Q

Describe the systemic circuit of the cardiovascular pathway.

A

The largest artery in the systemic circuit, the aorta, receives blood from the heart. The largest veins, the superior and inferior venae cavae, return blood to the heart.

19
Q

What does the hepatic portal system do?

A

The hepatic portal system drains blood from the capillary beds of the digestive tract to a capillary bed in the liver. It also purifies blood of toxins and pathogens. After blood has filtered through the liver, it is collected by the hepatic vein and returned to the inferior vena cava.

20
Q

At what point does lymph return to the general blood circulation?

A

Osmotic pressure and blood pressure control movement of fluid through the capillary wall. Fluid tends to move from the capillaries into the tissue spaces. Excess interstitial fluid left behind in capillary beds is collected by lymphatic vessels. This fluid is called lymph and is returned to the venous blood in the shoulder region.

21
Q

Briefly describe the following cardiovascular disorders: hypertension, atherosclerosis, stroke, heart attack, aneurysm, angina pectoris.

A

Cardiovascular disease is the leading cause of untimely death in Western countries.
Disorders of the Blood Vessels
Disorders of the blood vessels include hypertension and atherosclerosis, which often lead to a stroke, heart attack, or aneurysm.

High Blood Pressure (hypertension) is high blood pressure, which can lead to heart disease. The best defense against hypertension is a lifestyle that lowers the risk of hypertension. (See p. 106 in text for health tips on preventing cardiovascular disease.)

Atherosclerosis is an accumulation of fatty cholesterol plaque in the linings of arteries. There is a tendency for blood clots to form on these plaques. A stationary clot is called a thrombus. If the clot breaks loose and travels, it is called an embolism. If an embolism lodges in a small blood vessel (especially in the heart, lungs, or brain), the thromboembolism is life-threatening.

Stroke, Heart Attack, and Aneurysm
If a blood clot lodges in a cerebral blood vessel or a cerebral blood vessel bursts, a stroke has occurred and a portion of the brain dies. If a blood clot lodges in a coronary blood vessel, a heart attack occurs. An aneurysm is a ballooning of a blood vessel. If a major blood vessel like the aorta bursts, death is likely. Blockage of a coronary artery can cause angina pectoris.

22
Q

What is the reason that many doctors recommend that some patients take a baby aspirin each day?

A

There are medical treatments for dissolving and perhaps preventing the occurrence of blood clots. A biotechnology drug, t-PA, is used for this purpose. Aspirin can also lower the probability of clot formation.

23
Q

Name two ways to treat clogged arteries.

A

In a coronary bypass operation, a vessel is grafted onto the heart to bypass an obstructed vessel. Angioplasty is also a common surgical procedure for treating clogged arteries. Gene therapy has also been used to grow new blood vessels.

24
Q

What are some medical procedures to treat heart failure?

A

In heart failure, the heart no longer pumps as it should. Various medical procedures assist the heart in pumping and in regulating the heartbeat, including the implantation of a cardioverter-defibrillator to sense abnormally slow or fast heartbeats beneath the skin of the chest.

Heart Transplants
Heart transplants are routinely performed, but there is a shortage of human hearts. A left ventricular assist device (LVAD), implanted in the abdomen, is an alternative to a heart transplant. Work still goes forward on an artificial heart.