Chapter 5 Flashcards
Where are membranes found?
Surrounding the outside of a cell
Found inside a cell surrounding an organelle
What are the 4 main roles of a membrane?
Compartmentalisation- separating out areas for specific conditions
Site of chemical reactions- holds proteins involved in certain reactions
Cell signalling- membranes contain receptors that can lead to a response
Barrier- partially permeable membranes- controls what goes in/out
Why is it called fluid in the mosaic model?
This is because the phospholipids are free to move within the layer relative to each other.
Why is is called mosaic in the fluid mosaic model?
The proteins randomly embedded in the bilayer are different sizes and shapes.
What are intrinsic proteins?
Transmembrane proteins that are embedded through both layers of the membrane.
Held in place due to the interaction between R groups and the hydrophobic core of the membrane.
Role- transport across the membrane.
What are channel proteins?
Hydrpphillic channel
Passive movement of polar molecules and ions
Down concentration gradient
What are carrier proteins?
Passive transport
Active transport
Into cell
Shape of protein changes
What are glycoproteins?
Embedded in the cell-surface membrane
Has a carbohydrate attached
Role- cell adhesion
Role- receptors for hormones
Role-cell signalling
Role-act as antigens for cell recognition
Role- attach to water molecules
What are glycolipids?
Lipids with attached carbohydrate chain.
Role- Cell marker recognised by the immune system as self or no self.
What are extrinsic proteins?
Only present one side of the membrane
Loosely attached so can easily be displaced from the membrane
Hydrophilic R groups which interact with polar heads of phospholipids/intrinsic proteins
What is cholesterol?
A lipid with a hydrophilic head and a hydrophobic end.
Role: it binds to phospholipids phosphate heads, increasing the packing of the membrane, reducing the fluidity of membrane. Regulates the fluidity/stability of membranes.
How it stays in place?
Hydrophobic end interacting with tails.
Hydrophilic end interacting with the heads.
Pulling them together
How does temperature affect membrane structure?
Increased kinetic energy will lead to the breaking of weak intermolecular forces between fatty acids tails. This will lead to an increase in the permeability.
The increased kinetic energy will also denature channel and carrier proteins and this will affect the permeability.
How does solvent affect membrane structure?
It can enter the phospholipid blister and disrupt the interactions between fatty acid tails.
This will increase the permeability and fluidity and will break the membrane.
Why is diffusion?
It is the passive net movement of particles down the concentration gradient, until equilibrium is reached.
Can diffusion occur across a membrane?
Diffusion can occur without a membrane.
Particles can diffuse through a membrane without assistance if they are non-polar.
Polar particles need a protein channel to move through a membrane.