Chapter 5 Flashcards

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1
Q

IDETNIFY FIVE ROLES OF SURFACE MEMBRANES AT THE SURFACE OF CELL.

A

Separates cells from external environment.
Has antigens, so body’s immune system can recognise it as self.
Controls what goes into and out of the cell.
Communicates with other cells with hormone receptors etc. Site of chemical reactions.
May contain enzymes involved in specific metabolic pathways.

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2
Q

WHAT IS THE ROLE OF PLASMA MEMBRANES WITHIN CELLS?

REFER TO MITOCHONDRIA AND CHLROPLASTS.

A

Compartmentalisation.
In mitochondria, the inner membrane is called the cristae. This increases the surface area for respiration.
In chloroplasts the thylakoid membrane stores chlorophyll for photosynthesis.

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3
Q

WHAT IS THE FLUID MOSAIC MODEL?

A

This describes the structure of the plasma membrane as a mosaic of components

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4
Q

WHAT ARE EXTRINSIC MEMBRANE PROTEINS?

A

Peripheral proteins present in one side of the bilayer.
Have hydrophilic R-groups that interact with the polar heads of the phospholipids or with intrinsic proteins.
This can be in either layer and some can move between layers.

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5
Q

WHAT ARE INTRINSIC MEMBRANE PROTEINS?

A

Contain amino acids with hydrophobic R-groups on external surfaces which interact with the hydrophobic core keeping them in place.

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6
Q

WHAT ARE CHANNEL PROTEINS

A

Provide a hydrophilic channel that allows diffusion of polar molecules and ions.

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7
Q

WHAT ARE CARRIER PROTEINS

A

Facilitate both passive and active transport. This can change shape using ATP to allow the molecule to pass.

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8
Q

WHAT ARE GLYCOPROTEINS?

A

Embedded in the membrane with carbohydrate chains. Allows cell adhesion.
Acts as a receptor for chemical signals.

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9
Q

WHAT ARE GLYCOLIPIDS

A

Lipids with attached carbohydrate chains. These are antigens and allows cell recognition.

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10
Q

WHAT IS THE PURPOSE OF CHOLESTEROL IN THE BILAYER?

A

Regulates the fluidity of membranes.
It adds stability without making them too rigid.
Prevents the lipid solidifying by stopping the phospholipid from grouping too closely and crystallising.

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11
Q

HOW DOES DIFFUSION ACROSS MEMBRANES OCCUR?

HOW IS EQULIBRIUM MAINTAINED?

A

Passive process which takes advantage of the particles’ natural kinetic energy. Particles move down a concentration gradient and eventually are all equally spread out, equilibrium is reached.
The equilibrium is maintained, when molecules enter the cell they move to their required place so the flow is kept constant. E.g. water moves to the mitochondria to start respiration.

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12
Q

HOW DOES SIMPLE DIFFUSION OCCUR FOR LIPIDS AND MSLL POLAR MOLECULES.

A
  • NON-POLAR MOLECULES: travel down freely
    • LIPIDS SOLUBLE: dissolve in the bilayer and can travel freely across.
    • POLAR MOLECULES: repelled by hydrophobic interior.
      WATER: an exception. It is so abundant that some water can travel down by diffusion. But it’s quite slow.
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13
Q

HOW DOES FACILIATED DIFFUSION WORK?

A

Polar molecules cannot pass by simple diffusion. They need facilitated diffusion to help them pass. They go through protein channels. This is still a passive process but requires the use of channels which provide a path by which the molecules can pass.

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14
Q

WHAT ARE 5 FACTORS AFFECTING DIFFUION RATE?

A
  • TEMPERATURE:
  • DIFFUSION DISTANCE:
  • SURFACE AREA:
  • SIZE OF DIFFUSING MOLECULE:
  • CONCERTATION GRADIENT:
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15
Q

HOW DOES OSMOSIS WORK?

A

The net diffusion of water from an area of high water potential to an area of low water potential down a water potential gradient.
When solute is added to water the water potential is lowered because the molecule binds to the water, less water molecules are ‘free’.

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16
Q

WHAT IS WATER POTENTIAL

A

measure of the tendency of water molecules to diffuse from one region to another.
- Pure water has highest water potential at 0Kpa.
- When solutes are added water potential is lower (goes negative)
- If solutions are separated by a partially permeable membrane, the net movement of water will be from the side with higher water potential to the side with lower potential .
Water potential of both plant and animal cells is lower than pure water:

17
Q

WHEN DOES A CELL BECOME CYTOLYSED?

A

When too much water enters and animal cell causing it to burst.

18
Q

WHEN DOES A CELL BECOME CRENATED

A

When water leaves the animal cell causing it to shrivel.

19
Q

WHEN DOES A CELL BECOME TURGID

A

When too much water enters a plant cell the vacuole is pushed against the cell wall causing it to become firm.

20
Q

WHEN DOES A CELL BECOME PLASMOLYSED?

A

When water leaves a plant cell, the cell membrane pulls in from the cell wall causing it to become flaccid.

21
Q

HOW DOES ACTIVE TRANSPORT WORK?

A

Moving substances against the concentration gradient requires energy. ATP is hydrolysed into ADP and a phosphate. The ions enters the channel. Phosphate binds to channel causing to change shape. Channel opens up to the other end allowing ions to pass through. ADP is re-joined with the phosphate making ATP again.

22
Q

WHAT ARE CARRIER PROTEINS?

A

Have very specific shapes to let only a certain molecule through. Use the above mechanism for this process.

23
Q

WHAT IS BULK TRANSPORT?

A

Sometime, molecules are either too large or are in large quantities and can’t pass by diffusion.

24
Q

WHAT IS ENDOCYTOSIS?

A

AKA phagocytosis. Basically eating solid matter

25
Q

WHAT IS EXOCYTOSIS?

A

Pooping stuff out.

26
Q

WHAT IS PINO….CYTOSIS?

A

If its liquids.

27
Q

HOW DOES TEMPERATURE AFFECT THE RATE OF TRANSPORT THROUGH THE PLASMA MEMBRANE?

A

Increasing temperature, increases the kinetic energy. This means the particles of the membrane vibrate and become weakened and so more permeable. High temperatures also cause lipids to melt decreasing stability of the structure and causing it to be more permeable.
When temperature drops saturated fatty acids pack together. The unsaturated fatty acids maintain fluidity by providing kinks in the structure. Cholesterol also buffers the fluidity.
Proteins are not as stable as lipids. When the temperature increases the enzymes tertiary structure is affected. If it is too high it will denature.

28
Q

HOW DOE SOLVENTS AFFECT PERMEABILITY?

A

Solvents dissolve the lipids affecting permeability.