Chapter 46 - Mucinoses

Question 1

True or false: mucin is a jelly-like amorphous mixture comprised of neutral glycoaminoglycans that’s produced by fibroblasts.

Answer 1

False; mucin is a jelly-like amorphous mixture comprised of ACID glycoaminoglycans that’s produced by fibroblasts.

Question 2

True or false: mucin is capable of absorbing 1000 times its own weight in water.

Answer 2

True

Question 3

List four stains that will highlight mucin.

Answer 3

Alcian blue, colloidal iron, toluidine blue, mucicarmine

Question 4

Is mucin PAS negative or positive?

Answer 4

PAS negative because PAS stains neutral glycoaminoglycans, and mucin is comprised of acid glycoaminoglycans

Question 5

True or false: the firm waxy papules that are seen in scleromyxedema often have a strikingly annular array.

Answer 5

False; they often have a strikingly linear array

Question 6

Are the mucous membranes and scalp involved in scleromyxedema?

Answer 6

No, they’re spared