chapter 4.2 and 4.3 Flashcards
What are the methods of movement across a membrane
Passive transport (diffusion and facilitated diffusion)
Active transport
Osmosis
Active and passive what’s are difference due to
- If substances require energy to move them it is called active transport.
- If substances do not require energy to move them it it called passive transport. Diffusion is an example of passive transport.
Diffusion is defined as
the net movement of molecules or ions from a region where they are more highly concentrated to one where their concentration is lower until evenly distributed.
Net movement
all particles move at random in diffusion, it’s just that more move in one direction than in the other. This is due to concentration difference. So therefore the net movement would be toward the area where there is higher concentration, as diffusion moves from high to low concentration.
Examples of substances that can diffuse freely across the bilayer
- Small like oxygen and carbon dioxide can diffuse around the cell membrane. .
- hydrophobic substances
- soluble in lipids so can pass through the phospholipid bilayer
- non-polar molecules like oxygen and carbon dioxide
- however, small, polar molecules like water and urea also diffuse across, but much more slowly
Examples of substances that cannot diffuse across the bilayer
Charged particles are unlikely to diffuse across a membrane, even if they are very small.
Molecules that diffuse through membrane with the assistance of transport protein
- Hydrophilic substances like water molecules
- large molecules
- polar molecules diffuse through membrane due tot the hydrophobic nature of the fatty acid tails
Is facilitated diffusion a passive process
Yes
Two types of protein molecules are involved
protein channel and carrier protein
What job do protein channels do
- These proteins form water-filled hydrophilic channels across the membrane.
- They allow specific water and water-soluble ions to pass through, such water and ions.
Are protein channels selective
yes each opening in the presence of a specific ion, or in response to a specific messenger or a change in voltage across the membrane. If the particle ion is not present, the channel remains closed
Why are protein channels selective
So there is control over the entry and exit of ions. The ions bind with the protein causing it to change shape in a way that closes to one side of the membrane and opens it to the other side.
How do protein channels and carrier proteins bind with their specific ion and transport it across the membrane
The specific molecules temporarily binds with the protein it causes it to change shape. This causes it to change shape in such a way that it closes to one side of the membrane releasing it to the inside of the membrane and closes to the other of the membrane.
Can carrier proteins move molecules in either direction
yes
Is a carrier protein a passive form of transport
Yes it requires no external extra energy except only on the inbuilt motion of kinetic energy of the diffusing molecules
Why are all protein channels and carrier proteins only specific to one type of molecule
All protein channels and carrier proteins have specific tertiary structures, this means one particular type of ion or molecule can pass through or bind with them, as they have to be complementary to the shape of the tertiary structure.
what does Fick’s law show
It describes the relationship between the rate of diffusion (how fast diffusion is) and three factors that effect surface area, concentration gradient and thickness of membrane. It states that rate of diffusion is proportional (as one factor goes up the other factor goes up) to surface area and concentration difference and is inversely proportional (as one factor goes up the other goes down) to the thickness of the membrane
What is Fick’s law
that rate of diffusion is proportional to:
Surface area x difference in concentration
————————————————————-
length diffusion path (membrane thickness)
Increasing thickness of the cell membrane will
- I decrease the rate of diffusion.
- Increasing the surface area across of the cell membrane will increase the rate of diffusion
- The rate of diffusion is directly proportional to the surface area and difference in concentration but indirectly proportional to the length of diffusion path.
Increase surface area across the cell membrane will
increase the rate of diffusion
- The rate of diffusion directly proportional to?
- The rate of diffusion indirectly proportional to?
- What does proportional mean?
- What does indirectly?
- increase surface area and difference in concentration difference
- length of diffusion path (thickness)
- As one factor goes up the other factor will go up
- As one factor goes up the other factor goes down
Is diffusion rapid in gases and can it occur in solids
yes diffusion is very rapid in gases and it can occur in solids but just not as fast
what is used to mimic the cell membranes
Visking tubing is used in the lab to mimic the cells membrane.
What is the definition of osmosis
the passage of water from a region where it has a higher water potential to a region where it has a lower water potential through a selectively permeable membrane.