chapter 4.1 Flashcards
L-dopa
penetrates the blood-brain barrier and is converted to dopamine once inside the brain.
membrane potential
difference in electrical charge between the inside and the outside of a cell.
to record a neuron’s membrane potential
you must position the top of one electrode inside the neuron and the tip of another electrode outside the neuron in the extracellular fluid.
microelectrodes
intracellular electrodes.
resting potential
steady membrane potential of about -70 mV; said to be polarized.
ions
positively and negatively charged particles.
in resting neurons
there are more Na+ ions outside the cell than inside, and more K+ ions inside than outside.
ions channels
specialized pores in neural membranes through which ions can pass. Each type is specialized for the passage of particular ions.
electrostatic pressure
the -70 mV charge attracts the positively charge Na+ ions into resting neurons.
random motion
pressure for Na+ ions to move down their concentration gradient.
sodium-potassium pumps
Hodgkin and Huxley; mechanisms in the cell membrane continually exchange three Na+ ions inside the neuron for two K+ ions outside.
transporters
mechanisms in the membrane of a cell that actively transport ions or molecules across the membrane.