Chapter 4 - Renal Transport Mechanisms - NaCl and Water Reabsorption along the nephron

Question 1

Na+ reabsorption by the proximal tubule is a good example of transport by the ________ pathway.

Answer 1

Na+ reabsorption by the proximal tubule is a good example of transport by the transcellular pathway.

Question 2

The reabsorption of Ca++ and K+ across the proximal tubule is a good example of _________ transport.

Answer 2

The reabsorption of Ca++ and K+ across the proximal tubule is a good example of paracellular transport.

Question 3

The key element in proximal tubule reabsorption is the _____ and it is located in _______.

Answer 3

The key element in proximal tubule reabsorption is the Na+-K+-ATPase pump in the basolateral membrane.

Question 4

Na+ is reabsorbed by different mechanisms in the first and the second halves of the proximal tubule. In the first half of the proximal tubule, Na+ is reabsorbed primarily with _____ and a number of other solutes (e.g., glucose, amino acids, Pi, and lactate).

Answer 4

Na+ is reabsorbed by different mechanisms in the first and the second halves of the proximal tubule. In the first half of the proximal tubule, Na+ is reabsorbed primarily with HCO3- and a number of other solutes (e.g., glucose, amino acids, Pi, and lactate).

Question 5

Na+ is reabsorbed by different mechanisms in the first and the second halves of the proximal tubule. In the second half, Na+ is reabsorbed mainly with ______

Answer 5

Na+ is reabsorbed by different mechanisms in the first and the second halves of the proximal tubule. In the second half, Na+ is reabsorbed mainly with Cl−.

Question 6

Changes in Na+ reabsorption influence the reabsorption of water and other solutes by the proximal tubule. This point is especially relevant during volume depletion when increased Na+ reabsorption by the proximal tubule is accompanied by a parallel increase in HCO3- reabsorption, which can lead to ____________.

Answer 6

Metabolic Alkalosis