Chapter 4 - Preferred Risk Underwriting Flashcards
What was the goal of the Framingham Heart Study?
To identify risk factors for CAD
What did volunteers of Framingham study agree to?
They had an initial exam (to include med hx, physical measurements such as height, weight, and BP, resting EKG, chest x-ray, and blood chemistries). They are re-examined every 2 years.
When did preferred product offerings sweep the industry?
Late 1980s and early 1990s
What is the goal of multivariate regression?
To separate out and quantify the influence of each risk factor according to its own independent contribution to risk.
How should underwriters think of weights in equations?
As the correct number of debits or points assigned to a variable
What does a hazard ratio (HR) of 1.0 mean?
No change in risk from the referent baseline (1 = 100%). If HR ratio > 1, it is like an underwriting debit. If < 1, like a credit
What is a dependent variable?
The target variable of interest (such as heart disease in the Framingham study)
How are Cox regression coefficients reported?
Over base “e” so if coefficient is reported as 0.14, this means e^0.14
How do you convert a Cox coefficient to an HR?
in Excel, you type =exp( ) and put the coefficient in parentheses
How do you convert an HR into a coefficient?
use formula =ln( ) and put the HR in the parentheses
How to measure HR for a 2 unit change?
Ex: Coefficient of chol is 0.14 and there is a 2 unit change in chol. What is the HR?
0.14*2 = 0.28 ——> =exp(0.28) = 1.32 HR
Or you can just use the unit change # as an exponent. HR using 0.14 in exp(0.14) is 1.15. 1.15^2 is 1.32
What are the two preferred risk stratification models?
Point system and knock-out system
How does the point system work?
All risk factors are assigned points and summed, the lower the number the better the risk
Which preferred risk model is superior?
The point system
How does the knock out system work?
Preferred criteria are a series of rules associated with each factor, and if the PI does not meet the criteria, they are knocked out of the the preferred class