Chapter 4: General Surgery Flashcards
How do you diagnose GERD when it’s ambiguous?
pH monitoring
When do you do surgery for GERD?
if complications have developed:
- ulceration
- stenosis
What’s the usual procedure that’s done for GERD?
Nissen fundoplication
Clinical pattern of motility problems?
crushing pain with swallowing in uncoordinated massive contraction
Pattern of dysphagia in achalasia?
solids are swallowed w less difficulty than liquids
How do you diagnose achalasia?
- barium swallow
2. manometry (diagnostic)
Most common treatment for achalasia?
balloon dilation by endoscopy
Presentation of cancer of esophagus?
- dysphagia starting with meat–> then other solids –> soft foods –> liquids–> saliva
- significant weight loss
Types of esophageal cancer?
- squamous cell carcinoma: seen in male smokers and drinkers
- adenocarcinoma: long-acting GERD
What should you do before endoscopy in diagnosing esophageal cancer to avoid inadvertent perforation?
barium swallow
How can you assess operability in esophageal cancer?
CT scan
Typical management for esophageal cancer?
palliative, most cases aren’t good for surgery
Diagnosis and treatment of mallory-weiss tear?
endoscopy and photocoagulation respectively
Sx of Boerhaave Syndrome
- prolonged, forceful vomiting
- continuous, severe epigastric pain + low sternal pain of sudden onset
- fever
- leukocytosis
Dx of Boerhaave Syndrome?
Contrast swallow:
- Gastrografin
- Barium
Tx of Boerhaave Syndrome?
surgical repair
Sx of gastric adenocarcinoma?
anorexia weight loss vague epigastric distress early satiety occasional hematemesis
Gastric adenocarcinoma diagnosis and treatment?
Dx: endoscopy and biopsies, CT to assess operability
Tx: surgery
Sx and diagnosis Gastric lymphoma?
similar to gastric adenocarcinoma
Gastric lymphoma tx?
surgery if you fear perforation as the tumor melts away
low-grade MALTOMAs can be reversed by eradicating H. pylori
initial treatment of mechanical small bowel obstruction?
NPO
NG suction
IV fluids
How long do you wait for resolution of complete sbos?
24 hs
how long do you wait before surgically treating a partial sob?
a few days
Difference bw bowel obstruction and strangulated obstruction?
strangulated= sbo sx + fever, leukocytosis, constant pain, signs of peritoneal irritation, and full-blown peritonitis and sepsis
Treatment for strangulated obstruction?
emergency surgery
Incarcerated hernia vs strangulated obstruction?
incarcerated hernia= irreducible hernia that used to be reducible
Carcinoid syndrome:
=small bowel carcinoid tumor with liver metastases
- diarrhea
- flushing of the face
- wheezing
- right-sided heart valve damage (look for prominent JVP)
What will be prominent in 24h urine collection of people with carcinoid syndrome?
5-hydroxyindoleacetic acid
Sx of anorexia?
- vague periumbilical pain
- sharp, severe, constant pain localized to the right lower quadrant of the abdomen
- tenderness, guarding, rebound in the right lower quadrant of the abdomen (not elsewhere in the belly)
- modest fever
- leukocytosis: 10,000-15,000 range
- neutrophilia and immature forms
What do you use to diagnose acute appendicitis when you’re not 100% certain of the diagnosis?
CT scan
Cancer of the Right Colon Sx:
- anemia (hypochromic, Fe defic) in elderly
- 4+ stools for occult blood
- Dx: colonoscopies and biopsies
Tx for right colon cancer?
right hemicolectomy
Cancer of the left colon Sx:
- bloody bm (blood coats outside of stool)
2. constipation + stools of narrow caliber
Dx of left colon cancer?
- flexible proctosigmoidoscopic exam (45-60 cm)
2. biopsies
What must you do before surgery of left colon cancer?
full colonoscopy to r/o synchronous second primary
Tx of left colon cancer?
- surgery
2. pre-op chemotherapy + radiation for large rectal cancers
Colonic Polyps: descending order of probability of malignant degeneration
- familial polyposis (and variants such as Gardners)
- familial multiple inflammatory polyps
- villous adenoma
- adenomatous polyp
Non-malignant colonic polyps:
- Juvenile
- Peutz-Jeghers
- isolated inflammatory
- hyperplastic
Chronic ulcerative colitis (CUC) Tx:
medically managed
Chronic ulcerative colitis indications for surgery?
- disease present for longer than 20 years (high incidence of malignant degeneration)
- severe interference w nutritional status
- multiple hospitalizations
- need for high-dose steroids or immunosuppressants
- development of toxic megacolon (abdominal pain, fever, leukocytosis, epigastric tenderness, massively distended transverse colon on x-ray w gas wi wall of colon)
Definitive surgical treatment of chronic ulcerative colitis?
remove affected colon + all of the rectal mucosa (always involved)
Current most common abx that causes pseudomembranous enterocolitis?
cephalosporins
How to dx C-diff?
identify toxin in the stool
stool cultures too long, pseudomembrane not always seen on endoscopy
C-diff Tx of choice:
metronidazole
vancomycin (alternate)
What presentation in C diff requires emergency colectomy?
form that’s unresponsive to treatment
wbc >50,000
lactate >5
How to r/o cancer in all anorectal diseases?
proper physical exam (including proctosigmoidoscopic exam)
Internal hemorrhoids:
typically bleed when they’re internal
treat w rubber-band ligation
can become painful or itchy if they prolapse
External hemorrhoids;
typically hurt
surgery if conservative treatment fails
Who usually gets anal fissure? Sx?
young women
exquisite pain w defecation
blood streaks the stools
(may need to do physical exam under anesthesia to see fissure)
Typical location of anal fissure?
posterior midline
Cause of anal fissure? Tx?
tight sphincter Tx: 1. stool softener 2. topical nitroglycerin 3. local injection of bolulinum toxin 4. forceful dilation 5. lateral internal sphincterotomy 6. calcium channel blocker (diltiazem ointment 2% TID) for 6 weeks: 80-90% success rate
Sign of Crohn’s disease?
fissure, fistula, or small ulceration that fails to heal and gets worse after surgical intervention *this area typically heals really well bc of excellent blood supply)
Should you do surgery on Crohn disease of anus?
NO!
if fisula is present: drain w setons while medical therapy is underway + remicade helps healing
Ischiorectal abscess sx:
- febrile
- exquisite perirectal pain that can’t sit down or have a bm
- classic findings of abscess: rumor, dolor, cal or, tumor (lateral to the anus bw the rectum and ischial tuberosity)
Tx of ischiorectal abscess?
Incision and Drain
make sure to do physical exam for cancer first!
In diabetics, watch for horrible necrotizing soft tissue infection
Fistula-in-ano
seen in some its who have had an ischiorectal abscess drained
- epithelial migration from the anal crypts (where abscess originated)
- epithelial migration from the perineal skin (where the drainage was done) form permanent tract
Fistula-in-ano presentation:
- pts complain of fecal soiling + occasional perineal discomfort
- Physical exam: opening lateral to the anus w cordlike tract and discharge that is expressed
Tx of fistula-in-ano?
r/o necrotic and draining tumor
treat with fistulotomy
Who gets squamous cell carcinoma of the anus?
HIV+ individuals
homoseuals w receptive sexual practices
Squamous cell carcinoma of the anus presentation + Dx?
fungating mass that grows out of the anus
metastatic inguinal lymph nodes felt
Dx with biopsy
Tx for squamous cell carcinoma of the anus?
Nigro chemoradiation protocol (5 weeks protocol has 90% success rate) + surgery (if residual tumor is there)
What proportion of GI bleeding originates from the upper GI tract?
3/4 cases
upper gi= from tip of nose to the ligament of Treitz
Where does the remaining 1/4 of cases of GI bleeding come from?
colon or rectum
very few originate from the jejunum and ileum
Etiology of GI bleeding that originates from the colon?
- angiodysplasia
- polyps
- diverticulosis
- cancer
* *all are diseases of old people**
Young person w GI bleeding, where is it coming from?
most likely the upper GI
Old person w GI bleeding, where is it coming from?
anywhere (“equal opportunity”)
Vomiting blood: where is it coming from?
upper GI (tip of nose to ligament of treitz) -same is true when blood is recovered by NG tube in pt who shows up w bleeding from rectum
Red blood per rectum work-up:
- *could come from anywhere in the GI tract (even upper GI bc could have transited too fast to be digested) **
1. pass an NG tube and aspirate gastric contents
- -> if blood–> means it’s an upper source
- -> if non-bilious–> can exclude territory from tip of nose to pylorus (duodenum could still be a source) –> do upper GI endoscopy –> if no blood and fluid is green (bile tinged), then entire upper GI has been excluded
Active bleeding per rectum when upper GI is excluded?
- Anoscopy first: to exclude bleeding hemorrhoids
* * colonoscopy NOT helpful in active bleeding (incoming blood obscures the field)
- -Two directions to go after r/o hemorrhoids–
* *One
a. look at rate of bleeding: if >2ml/min (1 unit of blood every 4 hrs) –> do angiogram which can find source and allow for hagiographic embolization
b. if bleeding is wait until bleeding stops and then do colonoscopy
c. for in-between cases–> do a tagged red-cell study (really slow study though)-> see if blood puddles somewhere–> can possibly do an angiogram then or if the tagged red cells don’t show up can plan a colonoscopy
d. if bleeding is not found to be in the colon–> do capsule endoscopy to localize the spot in the small bowel
Blood per rectum in a child:
Meckel diverticulum
1. do technetium scan first to look for ectopic gastric mucosa
Massive upper GI bleeding in stressed or polytrauma or complicated post-op pt? Dx? Tx? Px?
probably stress ulcers
- Dx: use endoscopy to confirm
- Tx: angiographic embolization
- Px: maintain gastric pH above 4
Acute abdomen: Perforation
- sudden onset
- constant, generalized, severe
- reluctant to move, very protective of abdomen
- signs of peritoneal irritation (tenderness, guarding, rebound)
- Dx: free air under the diaphragm in upright x-ray is confirmatory
Most common cause of perforation?
peptic ulcer perforation
Acute abdomen: obstruction
- sudden colicky pain
- pt moves constantly looking for a comfortable position
- few physical exam findings of peritoneal irritation limited to affected areas