chapter 4 and 5 Flashcards
Brain imaging techniques
PET
MRI
neurotransmitters
dopamine
GABA
Acetylcholine
Serotonin
glutamate
Norepinephrine
Endorphins
Dose-response relationship
Potency
Threshold
all of none
effective dose
lethal dose
Therapeutic index
safety margin
Therapeutic Index
ratio of lethal dose (LD) to effective dose (ED)
Safety margin
Dosage between effective dose and lowest toxic dose
Placebo effect
think you are getting one thing when you are getting something different
Administration of drugs
oral
injection
Inhalation
insufflation
tropic
subcataneous
drug tolerance
Drug disposition tolerance - gets used to getting rid of it quicker
Behavioral tolerance - ability to behave better
Pharmacodynamic tolerance - withdrawal
Drug Deactivation
a drug ceases to have an effect when it is excreted unchanged from the body or is chemically changed
Liver changes structure, excretion through urine or sometimes skin
Half-life
Drug is at 50% of going down or away
drugs
stimulants
Depressant
nicotine
opioids
Hallucinogens
marijuana
psychotherapeutics