CHAPTER 4 Flashcards
(41 cards)
nucleic acids
polymers specialized for storage, transmission, and use of genetic information
DNA
deoxyribonucleic acid; has deoxyribose; has thymine
RNA
ribonucleic acid; has ribose; has uracil
nucleotides
monomers for nucleic acid: pentose sugar + nitrogenous base + phosphate group
two forms of nitrogenous bases?
-pyrimidines: single ring
-purines: fused double-ring
types of pyrimidines
-Cytosine
-Thymine
-Uracil
types of purines
-Adenine
-Guanine
how are nucleotides linked?
-through phosphodiester bonds
-phosphate groups link the 3 carbon in one sugar to the 5 carbon in another sugar
-nucleic acids grow in the 5’-to-3’ direction
DNA base?
-purines: adenine (A) & Guanine (G)
-pyrimidines: cytosine (C) & thymine (T)
complementary base pairing
purines pair with pyrimidines by hydrogen bonding
-can also take place between RNA and DNA
RNA base
-single-stranded, but base pairing can occur between different regions of the molecule which results in 3D structures
-RNA has uracil (U) instead of thymine
DNA
-two strands form a double helix
-all DNA molecules have the same structure
-genetic information is carried in the sequence of base pairs
Transcription
DNA sequences are copied into RNA
Translation
RNA sequence specifies the sequence of amino acids in a polypeptide
gene expression
transcription + translation
replication
when DNA reproduce itself
what does DNA replication & transcription depend on?
it depends on the base-pairing properties of nucleic acids
genome
the complete set of DNA in an organism
genes
sequences of DNA that are transcribed into RNA
hereditary information
DNA carries hereditary information from one generation to the next; closely related living species have more similar base sequences than do species that are more distantly related
what DNA sequencing used for?
to trace evolutionary relationships
other roles for nucleotides?
-ATP: energy transfer in biochemical reactions
-GTP: energy source ini protein synthesis
-cAMP: essential in many processes, including hormone action
-carried in synthesis and breakdown of carbohydrates and lipids
spontaneous generation? who disproved it?
some forms of life arose from decaying matter; Francesco Redi disproved this in 1668
what experiment disproved spontaneous generation
an experiment by Louis Pasteur showed that microorganisms can arise only from other microorganisms