Chapter 3A: Neurophysiology: The Generation, Transmission, and Integration of Neural Signals Flashcards
Polarized
All living cells have an electrical charge that’s more negative on the inside than the outside
Resting membrane potential
-65mV
-charged particles are called anions
+ charged particles are called cations
Ions are dissolved in…
Fluid
Extracellular fluid: outside the cell
Intracellular fluid: inside the cell
Maintaining the membrane potential
Selectively-permeable ion channels
Electrostatic force
Diffusion
Sodium-potassium pump
Selectively permeable ion channels
These channels allow specific ions to pass through the cell membrane while blocking others. They are selective based on size, charge, or other properties.
Electrostatic forces/electrostatic pressure
If inside of cell is negative, then positive ions on outside are attracted to the inside
Opposite charges attract
Diffusion
Tendency of molecules to move from areas of high to low concentration to spread out evenly
Diffusion is the movement of particles (solute)
Sodium-potassium pump
It pumps 3 sodium ions for every two potassium ions pumped in
Na+, K+
- Potassium is more highly concentrated inside the cell, so diffusion wants to move them out
- The force of electrostatic pressure draws the potassium back in
- K+ reaches equilibrium potential when the forces moving K+ out of the cell equal the forces pulling them in
Equilibrium potential: -65mV - Sodium-potassium pump helps keep all of this in balance