Chapter 305 - Approach to the Patient with Disease of the Respiratory System Flashcards

1
Q

The diseases of the respiratory system fall into three main categories. Name them and choose which one is the most frequent. Can you give examples of specific disease that might fall into more than one of the previous categories?

A

(1) Obstructive lung disease, which is the most frequent
(2) Restrictive disorders
(3) Abnormalities of the vasculature
“Although many specific diseases fall into these major categories, both infective and neoplastic processes can affect the respiratory system and result in myriad pathologic findings, including those listed in the three categoreies above.”

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2
Q

What are the cardinal symptoms of respiratory disease?

A

Dyspnea and cough.

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3
Q

Patients might describe dyspnea differently, which can be suggestive of different pahotological processes. Make the correspondence between the expression used to describe dyspnea and what disease it might suggest: (a) “Chest tightness”; (b) “inability to get a deep breath”; (c) “air hunger”.

A

(a) , (b) - Pulmonary obstrutive diseases

(c) - Congestive heart failure

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4
Q

Dyspnea on exertion is an early symptom of underlying lung or heart disease.
True or False?

A

True.

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5
Q

In evaluating dyspnea on exertion there are two aspects that should be thoroughly investigated. What are those?

A

Determine the degree of exertion that causes dyspnea and/or adaptation of the patient to a new level of activity to accomodate their progressive limitation. The second aspect is fundamental since many patients limit their activity and do not complain about symptoms on exertion, simply because they limit their activity.

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6
Q

What is the cutoff for chronic cough?

A

More than 8 weeks.

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7
Q

Name the “nonrespiratory” causes of cough.

A

Gastrointestinal diseases (such as gastroesophageal reflux), cardiac diseases as well as psicogenic causes.

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8
Q

Which diseases are associated with chronic cough?

A

Obstructive lung diseases, particularly asthma and chronic bronchitis, aswell as gastroesophageal reflux, postnasal drip and intesticial pulmonary fibrosis.

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9
Q

The cough is usually productive in idiopathic pulmonary fibrosis.
True or False?

A

False.
“Diffuse parenchymal diseases, including intersticial pulmonary fibrosis, frequently present as a persistent, nonproductive cough.”

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10
Q

Pulmonary hypertension can be the cause of chest discomort.

True or False?

A

True.

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11
Q

Pulmonary chronic diseases might occur with left heart failure symptoms, due to cor pulmonale.
True or False?

A

False.

Cor pulmonale is due to overload to the right side of the heart.

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12
Q

Smoking habits might be associated with different lung diseases. Name four examples.

A

“Chronic Obstructive Pulmonary Disease and bronchogenic lung cancer but also a variety of diffuse parenchymal lung diseases (e.g., desquamative intersticial pneumonitis and pulmonary Langerhans cell histiocytosis).”

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13
Q

What should the physical examination should focus on if you suspect rheumatologic or autoimmune diseases with respiratory involvement?

A

Question should focus on joint pain or swelling, rashes, dry eyes, dry mouth, or constitutional symptoms.”

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14
Q

How do you distinguish pneumonia from pleural effusion on thoracic physical examination?

A

Palpation is a useful tool since tactile fremitus will be inscreased in the first and diminished in the former.

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15
Q

How do you distinguish pneumothorax from pleural effusion on thoracic physical examination?

A

Percussion is a useful tool in this setting since the sound will be hyper-resonant in the first and dull in the former.

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16
Q

What are the conditions associated with chronic ronchi?

A

Chronic obstructive pulmonary disease or bronchiectasis.

17
Q

How do you differentiate pathophysiologically wheezing from ronchi?

A

Wheezing results from obstruction of smaller-sized airways, being higher-pitched than ronchi, which are due to obstruction of mid-sized airways, most often with secretions.

18
Q

What is the pathophysiology of crackles? Which diseases might be associated with this finding?

A

Crackles are due to processes involving the alveoli.
This happens in alveolar diseases, pneumonia, pulmonary edema and intersticial diseases such as intersticial pulmonary fibrosis.

19
Q

How is it possible to differentiate between alveolar processes with fluid filling versus intersticial fibrosis on thoracic physical examination?

A

Consolidation (for example, due to fluid filling) is associated with egophony and pectoriloquy, aswell as auscultation of sounds from larger airways (for example, bronchic sound in a lung zone, where one would expect to hear vesicular breath sounds).

20
Q

Pulsus paradoxus is an ominous sign in pulmonary obstructive disease.
True or False?

A

True.
Pulsus paradoxus is the decrease of systolic arterial pressure >10mmHg with inspiration. It might be detected by palpation on brachial/femoral artery if the pressure has a decrease >15mmHg.

21
Q

What is the general value of FEV1/FVC (Forced Expiratory Volume in 1 second divided by Forced Vital Capicity) to define obstruction in spirometry?

A

Less than 70%.

22
Q

A plateau of the expiratory and inspiratory curves suggests large-airway obstruction in intrathoracic and extrathoracic locations, respectively.
True or False?

A

True.

23
Q

What is the value that defines restrictive pulmonary disease in the spirometry?

A

Total Lung capacity less than 80% adjusted to the patient’s age, race, sex and height, accompanied with symmetric decrease of FEV1 and FVC.

24
Q

The processes responsible for restrictive pulmonary disease are diverse. If the DLCO (diffusion capacity of the lung for carbon monoxide) is decreased, which group of diseases are suggested?

A

Parenchymal disease over chest wall, pleural or neuromuscular weakness. It can also be decreased in vascular disease.

25
Q

Normal spirometry and normal lung volumes with a low DLCO (diffusion capacity of the lung for carbon monoxide) suggests pulmonary vascular disease.
True or False?

A

True.