Chapter 2B: Transport Flashcards
What are the functions of cell membranes? (5)
- keeping all cellular components inside the cell
- partially permeable - lets certain mol. in and out of cell
- isolating organelles from the rest of the cytoplasm (allowing cellular processes to occur separately e.g- ER has a membrane)
- site of biochemical reactions (e.g- enzymes on inner membrane of mitochondria for respiration)
- allowing cells to change shape
What are the main two components of a plasma cell membrane?
proteins
phospholipid bilayer
What is the structure of a phospholipid?
phosphate head which is a polar molecule
2x fatty acid tail chain is non-polar
What 3 structures can be formed when phospholipids are placed in water and in what conditions?
-bilayer (water on two sides)
-monolayer (water/air interface)
-micelle (water/air interface)
draw structures!!!!
Can water soluble molecules pass directly through the membrane and why/why not?
water soluble mol. will NOT be able to pass through the membrane because they will not be able to pass through the hydrophobic fatty acid part of phospholipid bilayer
Can lipid soluble molecules pass directly through the membrane?
lipids are insoluble so no water will be near it so it can pass through the hydrophobic phospholipid part of membrane
Is the membrane flexible and why is this useful?
Phospholipids are held together by weak forces between the molecules making up the bilayer, the molecules can slide past each other and change position in the bilayer,
so it can allow the cell to change shape
What is the name of the model that the cell membrane is based off and why?
fluid-mosaic model
fluid because it exists in water and individual phospholipid molecules and proteins can diffuse within their monolayer and thus move around.
mosaic- different sized proteins randomly dotted around the membrane
What 3 types of proteins exist in the membrane (in terms of position)?
- extrinsic: outside membrane
- intrinsic: goes fully through the membrane
- partially intrinsic: goes partially through the membrane
What are glycoproteins?
- chains of carbohydrates that are attached to proteins
- chains that go straight out of cell
What are the functions of glycoproteins? (3)
- act as recognition sites (receptors) for HORMONES and NEUROTRANSMITTERS
- allow cells to recognise each other - lymphocytes can recognise each other (antigens)
- help cells to attach to each other to form tissues
What part of a glycoprotein/lipid acts as the receptor?
the carbohydrate part
What is a glycolipid?
carbohydrates bound to a lipid
curved branch
What are the functions of glycolipids? (3)
- acts as a recognition site for specific CHEMICALS
(e. g medication, alcohol) - helps maintain stability of membrane
- helps attach to each other to form tissues
How do glycolipids help maintain stability of the membrane?
they weigh down certain phospholipids to prevent them from moving too much
What is the function of cholesterol in the cell membrane?
- provides strength to membrane
- prevent water loss
- prevents ion loss
- reduces fluidity at high-temps
- reduces lateral movement of molecules in the membrane
What is a property of cholesterol?
they are VERY hydrophobic
What is lateral movement and why is this harmful?
when the top part of the phospholipid bilayer moves in one direction and the bottom part moves the other way
but this could destroy an intrinsic protein
What is diffusion?
it is the net movement of molecules in a fluid from an area of high concentration to an area of low concentration (down a concentration gradient). it is a passive process, no energy is required
What factors affect the rate of diffusion? (3)
- concentration gradient- higher the conc. gR, the higher the rate of diffusion
- thickness of exchange surface- thinner the material, the lower the distance that has to be travelled by particles, faster the rate
- surface area- larger the SA, faster the rate
How is the energy provided for passive transport processes?
by the inherent kinetic energy of the particles that are constantly moving in random directions, these particles collide with each other
What are the properties of a particle that allows it to diffuse faster?
smaller, can pass through the membrane and fit through the gaps more easily
lipid soluble, so that it can pass through the hydrophobic, non-polar fatty acid part of membrane
polarity, more polar a mol. is , it cannot pass through the non-polar part of the fatty layer chain