Chapter 298 : Hypoparathyroidism Flashcards
Which effect of PTH as the most influence on calcemia ?
Renal effect
Etiology hPTH ?
Neck surgery
Trauma
Immune mediated
Breeds predisposed to hPTH?
Miniature Schnauzer, Poodles, GSD, Terriers
Physical exam hPTH?
Neuro : Seizures, tremors, fasciculation
Behavioural changes : biting at paw, rubbing
Hyperthermia, stiff gait, painful when touch
Hearth: tachyarrythmias
Eye : lenticular cataract
Calcemia ?
Clinical signs observed when iCa < 0,8 mmol/L (might be observed at higher value if acute)
Acute treatment ?
In tetanic dog, Ca gluconate 0,5 - 1,5 ml/kg over 10 min
SC treatment ?
Risk of calcinosis cutis, not recommanded anymore
PTH treatment ? Chronic treatment
PTH Not commercially available
Calcitriol : 20 - 40 ng/kg/day for 4 days, then 10 - 20 ng/kg/day
Shorter life time than ergocalciférol
Oral calcium should be provided initially then tappered after 1 week of calcitriol