CHAPTER 28 Flashcards

1
Q

decreased RBC count

A

Anemia

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2
Q

slightly immature neutrophil

A

band cell

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3
Q

Primitive WBC

A

Blast cell

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4
Q

development of functions and characteristics that are different from those of the parent stem cell

A

differentiation

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5
Q

proteins produced by leukocytes that are vital to regulation of hematopoiesis

A

Cytokines

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6
Q

a cellular component of blood involved in transport of oxygen and CO2

A

Erythrocyte or RBC

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7
Q

process of formation of RBC

A

erythropoiesis

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8
Q

hormones produced by kidneys necessary for erythropoiesis

A

erythropoietin

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9
Q

filamentous protein; basis of thrombus and blood clot

A

fibrin

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10
Q

protein converted into fibrin to form thrombus and clot

A

fibrinogen

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11
Q

process of breakdown of fibrin clot

A

fibrinolysis

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12
Q

Granulated WBC (neutrophil, eosinophil, basophil)

A

granulocyte

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13
Q

percentage of total blood volume consisting of RBC

A

hematocrit

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14
Q

complex process of the formation of maturation of blood cells

A

hematopoiesis

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15
Q

iron-containing protein of RBC; delivers oxygen to tissues

A

hemoglobin

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16
Q

intricate balance between clot formation and clot dissolution

A

hemostasis

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17
Q

one of several cellular components of blood involved in defense in the body; subtypes include neutrophils, basophils, eosinophils, monocyte and lymphocytes

A

Leukocyte or WBC

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18
Q

less than normal amount of WBC in the circulation

A

leukopenia

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19
Q

form of WBC involved in immune function

A

lymphocyte

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20
Q

pertaining to lymphocyte

A

lymphoid

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21
Q

reticuloendothelial cell capable of phagocytosis

A

monocyte

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22
Q

pertaining to nonlymphoid blood cells that differentiate into RBCs, platelets, macrophages, mast cells, and various WBC

A

Myeloid

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23
Q

formation and maturation of cells derived from myeloid stem cell

A

myelopoiesis

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24
Q

lymphocytes that defend against microorganisms and malignant cells

A

Natural killer cells (NK)

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25
Q

fully mature WBC capable of phagocytosis; primary defense against bacterial infection

A

neutrophil

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26
Q

combined form of oxygen and hemoglobin; primarily found in arterial blood

A

Oxyhemoglobin

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27
Q

process of cellular ingestion and digestion of foreign bodies

A

phagocytosis

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28
Q

liquid portion of the blood

A

plasma

29
Q

protein converted to plasmin to dissolve thrombi and clots

A

plasminogen

30
Q

a cellular component of blood involved if coagulation

A

thrombocyte or platelet

31
Q

slightly immature RBCS, usually 1% of total circulating RBC

A

reticulocyte

32
Q

complex system of cells throughout the body capable of phagocytosis

A

reticuloendothelial cells

33
Q

portion of blood remaining after coagulation occurs

A

serum

34
Q

primitive cell, capable of self-replicating and differentiation into myeloid or lymphoid stem cell

A

stem cell

35
Q

component of bone marrow not directly related to hematopoiesis but serves important roles in this process

A

stroma

36
Q
  • a specialized organ that differs from other organs in that it exist in a fluid state
    -composed of plasma and various type of cells which account for 7-9% of total blood volume
A

blood

37
Q

55% of whole blood volume

A

plasma

38
Q

-it is the site for hematopoiesis
-one of the largest organ in the body, making up 4-5% of total body weight

A

Bone marrow

39
Q

-cellular component of blood is consist of 3 primary cells
make up to 40-45% of total blood volume

A

erythrocyte, leukocyte and thrombocyte

40
Q

-consist primarily of hemoglobin, which contains iron and protein and make up 95% of the cell mass
-no nuclei and have many fewer metabolic enzymes

A

mature erythrocytes

41
Q

cell-mediated immunity; recognizes material as foreign

A

t-lymphocytes

42
Q

Humoral immunity; forms antibodies

A

b-lymphocytes

43
Q

normal erythrocyte

A

biconcave disc

44
Q

total body iron content of the body

A

3g

45
Q

required for the synthesis of DNA

A

vitamin B12 and folate

46
Q

total leukocytes count

A

4,000 to 11,000 cells/mm3

47
Q

bright red granules

A

eosinophils

48
Q

deep blue stain granule

A

basophil

49
Q

pink to violet stain

A

neutrophil

50
Q

giant cells in the bone marrow is

A

megakaryocytes

51
Q

is particularly important for the maintenance of fluid balance within the vascular system

A

albumin

52
Q

normal lifespan of platelets

A

7 to 10 days

53
Q

most common test used in hematologic studies

A

CBC and peripheral blood smear

54
Q

platelets are restored in?

A
55
Q

removal of certain amount of blood under controlled conditions

A

therapeutic phlebotomy

56
Q

a single unit of whole blood contains how many ml?

A

450mL of blood and 50 mL anticoagulant

57
Q

platelet is restored in?

A

at a room temperature because they cannot withstand cold temperature and they last for 5days before they must be discarded

58
Q

plasma is restored in?

A

should be frozen; last for 1yr if it remains frozen

59
Q

a lyophilized, fee-dried concentrate of pooled fractionated human plasma used in treating hemophilia A

A

factor VIII concentrate

60
Q

a concentrated solution of antibody immunoglobulin (IgG), prepared from large pools of plasma

A

Immune globulin

61
Q

This method of transfusion may be initiated after surgery. about 1 to 2 units of blood are removed from the patient and simultaneously replaced with a colloid or crystalloid and the blood obtained may be reinfused after

A

hemodilution

62
Q

the whole blood or PRBCs are washed, often with saline; filtered and returned to the patient as an IV infusion

A

Intraoperative blood salvage

63
Q

is caused by antibodies to donor leukocytes that remain in the unit of blood or blood component

-chills and fever (after 2hrs of infusion)

A

febrile nonhemolytic anemia

64
Q

most dangerous and life-threatening, type of reaction

  • blood donor is incompatible with the recipient
    -cause of errors in blood component labeling, clerical error, error in patient identification
A

acute hemolytic reaction

65
Q

type of transfusion where in too much blood is infused too quickly, hypervolemia can occur.
-s/s dyspnea, orthopnea, tachycardia, high bp, jugular vein distention

A

transfusion-associated circulatory overload (TACO)

66
Q

is a potentially fatal, idiosyncratic reaction that is defined as development of acute lung injury occurring within 6hrs after blood transfusion

A

Transfusion-related acute lung injury (TRALI)

67
Q

occur within 14 days after transfusion, when the level of antibody has increased to the extent that a reaction can occur
-s/s fever, anemia, increased bilirubin level, absent haptoglobin, possibly jaundice

A

Delayed hemolytic reaction

68
Q

a rare fatal disease that causes irreversible brain damage

A

creutzfeldtz-jakob disease

69
Q

diseases potentially transmitted by blood transfusions

A

CMV, HIV, AIDS, HEPATITIS, GRAFT-VERSUS-HOST DISEASE (GVHD), CREUTZFELDT-JAKOB DISEASE