Chapter 27 Flashcards
Hypertensive disorders
Gestational hypertension
Preeclampsia (only cure deliver baby)
Eclampsia (only cure deliver baby)
Chronic hypertension
Common medical complication of pregnancy
- Complicates 5% to 10% of all pregnancies
- Rate of pregnancy-related hypertension has risen steadily since 1990 for all ages and ethnic groups
hypertensive disorders are a major cause of
prenatal death and IUGR (interuterine growth retardation)
10-15% of death
predisposing factors
- Family history
- Primagravida
- Pre-existing abnormality of vascular, metabolic or endocrine systems
- Hypertension
- Molar pregnancy- don’t have viable fetus (false pregnancy)
- Twins - more Hcg
- renal disease/renal problems
Morbidity
- Placental abruption (not during 3rd stage of labor)
- Cerebral hemorrhage
- Hepatic or renal dysfunction
- DIC (diminished intrmuscular cognation
- Pulmonary edema
- Seizures
Mortality
Pregnancy-related hypertension accounts for 10% to 15% of maternal deaths worldwide
Gestational hypertension
Onset of hypertension without proteinuria after week 20 of pregnancy
Systolic BP >140, diastolic BP >90 (have to have two different readings two different days)
-bp will return to normal 6 wks after delivery
Preeclampsia
Pregnancy-specific syndrome in which hypertension develops after 20 weeks of gestation in a previously normotensive woman
-move from preeclampsa to eclampsia when pt has a seizure
Eclampsia
- Onset of seizure activity or coma in a woman with preeclampsia
- No history of preexisting pathology
- 70% of eclamptic women develop the condition while pregnant
- 30% develop eclampsia in the immediate postpartum period (can still have seizure in postpartum period especially 1st 48 hours
chronic hypertension
Hypertension present before pregnancy or diagnosed before week 20 of gestation and persists after 6 weeks postpartum
Chronic hypertension with superimposed preeclampsia
Women with chronic hypertension may acquire preeclampsia or eclampsia
Preeclampsia etiology
A condition unique to human pregnancy
Signs and symptoms develop during pregnancy and disappear after birth
Preeclampsia Common risk factors:
- Primigravidity or new partner in this pregnancy
- Extremes of maternal age 35
- Multifetal pregnancy
- Obesity
- Preexisting medical condition
Preeclampsia pathophysiology
- Current thought: poor perfusion and endothelial cell dysfunction
- Arteriolar vasospasm diminishes diameter of blood vessels, which impedes blood flow to all organs and increases BP
- Main pathogenic factor is vasospasm and reduced plasma volume
- Decreased placental perfusion contributes significantly to restriction of fetal growth (less plasma volume so part of intrauterine growth retardation)
Vascular Damage patho
Platelet aggregation
Fibrin deposits
Hemolysis of RBC’s
Decreased placental blood flow & IUGR
Hypertension patho
Decreased vascular vol. & increased extravascular vol
Obstructed blood flow to liver & kidneys
Cerebral ischemia & CNS irritability.