Chapter 26 Flashcards
Genetic material
Nucleic acids, genetic code for instructions to make more virus particles
Capsid
Protein, protective structure that holds genetic code for virus
Lipid envelope
Lipid, additional protective layer around some viruses. Not as strong as capsid, can help virus better evade immune system
Matrix
Additional structural protein layer between capsid and envelope
Membrane glycoprotein
Interacts with feature on cell surface to find host cells. Sometimes facilitates entry
Gene therapy
Correction of defective or missing gene product by introducing genetic material in cells
Types of gene therapy
Inserting gene to compensate for nonfunctional gene
Swapping nonfunctional gene for normal gene
Repairing nonfunctional gene via selective reverse mutation
Altering regulation of particular gene
Why use viruses in gene therapy?
Viruses naturally invade cells to deliver RNA or DNA, can engineer viruses to deliver therapeutic gene of interest
Bacteriophage
Bacterial viruses, only infect bacteria. Have characteristic head-tail morphology