Chapter 20: Kidney, part 2

Question 1

Features of polyomavirus nephropathy

Answer 1

• nuclear enlargement with intranuclear inclusions

- interstitial inflammation

Question 2

What is the underlying cause of acute drug-induced interstitial nephritis?

Answer 2

-likely a hypersensitivity reaction with the drugs acting as haptens that bind to a tubular component and become immunogenic

Question 3

What are the features of analgesic nephropathy

Answer 3

• chronic tubulointerstitial nephritis

- renal papillary necrosis

Question 4

Conditions in which renal papillary necrosis is seen

Answer 4

• analgesic nephropathy
• diabetes mellitus
• sickle cell disease
• urinary tract obstruction
• renal tuberculosis

Question 5

Features of chronic urate nephropathy

Answer 5

-birefringent needle like crystals in tubules and/or interstitium