Chapter 20: Kidney, part 2 Flashcards

1
Q

Features of polyomavirus nephropathy

A
  • nuclear enlargement with intranuclear inclusions

- interstitial inflammation

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2
Q

What is the underlying cause of acute drug-induced interstitial nephritis?

A

-likely a hypersensitivity reaction with the drugs acting as haptens that bind to a tubular component and become immunogenic

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3
Q

What are the features of analgesic nephropathy

A
  • chronic tubulointerstitial nephritis

- renal papillary necrosis

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4
Q

Conditions in which renal papillary necrosis is seen

A
  • analgesic nephropathy
  • diabetes mellitus
  • sickle cell disease
  • urinary tract obstruction
  • renal tuberculosis
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5
Q

Features of chronic urate nephropathy

A

-birefringent needle like crystals in tubules and/or interstitium

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