Chapter 20 : Gram negative bacteria Flashcards
What are two important featuresthe bacteria about Neisseria (not its pathology)
They are cocci, usually diplocooci. They are oxidase positive
What is the value of the oxidase positive test for Neisseria?
It distinguishes them form the rGram negative pathogens
What are the two species of pathogenic Neisseria?
Neisseria Gonorrhoeae and Neisseria meninigitis
What are important symptoms of Gonarroea in men? Women? Babies?
Men: Pussy discharge
Women: Pelvic inflamatory disease: can cause sterility
Babies: Eye infection, inflation of the conductive. Ophthalmia neonate
What are features of Neisseria Gonorrea that contribute to its virulence?
Fimbriae and Capsules
What are the three most common meningitis causes bacteria?
Streptococcus pneumoniae
Neisseria meningititis
Haemophilus influenzae
What is the most common cause of meningitis in people under 20?
Neisseria meningitidis
What is a symptom of meningoccal septicemia?
Petechiae. It cause purple lesson and necrosis. It is the result of capillaries bursting.
What component of Gram negative bacteria are often responsible for their pathoginitciy?
Lipid A. It is an endotoxin.
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Which bacteria on our pathogens list are cloakrooms?
E. coli. Klebsiella, Serratia, (common but not on list enterobacter and ctirobacter)
What types of E. coli tend to be pathenogentic?
ETEC (Entertoxigenic E. coli)
Enterohemorriagic E. coli
Uropathonogenic e. Eoli (cause UTIS)
Descrie EHEC. What is its designation? How is it transmitted? What are kind of toxin does it have?
It is called E. coli 0157:H7
Ground beef, unpasteurized milk or fruit juice, produce.
It produces shingles like toxin.
What disease is cause by ETEC?
Gastroenteritits/ Traveler’s diarrhea
What disease are cause by EHEC (E. Coil 0157:H7)?
Hemorrhagic colitis, Kidney disorder (Hemolyitic uremic sydrome).
What aids in Klebsiella’s proliferation in the body? How you describe it’s pathogenicity?
Muccoid Capsules that help evade phagocytosis. It is an oppotunitic pathogen.
What diseases are can be cause by Klebsiella pneumonia?
Menigitisits, pnemonia, bacteremia, UTIs
Which enterbactericae can also be native microbiota?
Klebisella, E. Coli
How is Serrate most commonly acquired? By whom? What are trouble with treating it?
It is often by catheters and other hospital equipment. By immune compromised patentees. It is very resistant to antimicrobial drugs
Which two bacteria are associated with catheter? Which is most associated with long term use?
Serratia and Proteus mirabillis. P. mirabillis is most associated with long term catheter use.
Decirbe importnat info about Proteus.
Non coliform opportunistic enterbacteriaceae. Infections from catheters. Causes kidneys stone by raises pH from urease.
What are the truly pathogenic enteric bacteria?
Samonella typhimurium, Salmonella typhi, Shigella
What are the 4 gram negative bacilli or cocci bacilli the are not enteric covered in this class?
Hemophilis influenzae (does not cause flu), Bordetella pertussis, pseudomonas aeruginosa, Legionella pnemophila
What cause the plaque? What types are there How are they spread? What kind of bacteria is this?
Yersinia pestis. Bubonic, by fleas on rodents, pneumonic airborne person to person. The are loosly relate enteric bacteria.
How does salmonellosis work?
Salmonella attaches to the epithelial cells and trigger endocytosis. Multiples in endocytic vesicleIt kill hosts cell and endotoxins induce fever cramps, diarrhea, can get into the bloodstream.
Shigella is basically e. coli with bloody stool.. What toxin does it produce?
Shiga toxin.
What is the mechanism of shigellosis?
attaches to epithelial cells. Trigger endocytosis, multiplies in cytosol. Directly invades neighboring cells, avoiding the immunities system, Absecess form. No Bacteremia. Death from dared and dehydration.
What is the main disease cause by Haemophilus influenza? how has it’s transmission been reduced?
Meningitis. HIB vaccine.
Which gram negative bacillus has capsules?
Hemophilis influenzae (does not cause flu),
