Chapter 2 PPT - Neuroanatomy Overview + Basic Definitions Flashcards
Development of the nervous system:
the CNS is made up of the ______ + _______
brain + spinal cord
Development of the nervous system:
the PNS is made up of
- ______ + ______
- ______ + ______
- _____
- _____
- cranial nerves + ganglia
- spinal nerves + dorsal root ganglia
- ANS
- enteric nervous system (part of the ANS that innervated digestive organs)
Development of the nervous system:
At weeks 1-3 : the _______ develops from the amniotic sac. Forming the _____, ____, & _____.
embyronic disc
endoderm, mesoderm, ectoderm
Development of the nervous system:
At weeks _____ : the embryonic disc develops from the . Forming the endoderm, mesoderm, and ectoderm
1-3
endoderm
Development of the nervous system:
at weeks ____the ectoderm is developed from the _____ and forms our ____ and ______
weeks 1-3
embryonic disc → forms our skin + nervous system***
Development of the nervous system:
at weeks ____the mesoderm is developed from the _____ and forms our ____ and ______
weeks 1-3 , embryonic disc
forms our bones and muscles
Development of the nervous system:
at weeks ____the endoderm is developed from the _____ and forms our ____ and ______
weeks 1-3, embyronic disc
forms our respiratory + digestive systems
Development of the Nervous System: wks 1-3
Notochord = a cartilagenous tube that will eventually be absorbed into the spinal cord
Notochord develops from the _____ and stimulates the ectoderm to develop into the _____ , which eventually develops into the CNS and PNS
mesoderm
Neural plate
Development of the Nervous System: wks ____
______ = a cartilaginous tube that will eventually be absorbed into the spinal cord
_____ develops from the mesoderm and stimulates the _____ to develop into the _____ , which eventually develops into the ___ and ___.
weeks 1-3
notochord
Notochord, ectoderm, neural plate -→ CNS and PNS
Embryology Review:
The endoderm becomes: ____, ___, & ____
lining of digestive tract
columnar epithelial cells
liver cell
Embryology Review:
The mesoderm becomes: ____, ____, ____, & ____
bones + muscles
skeletal muscle, endothelial cells, cardiac muscle, RBC’s
Embryology Review:
The ectoderm becomes: ____, ___, & ____
skin + nervous system
Hair, Epithelial cells, neurons
Development of the Nervous system: weeks ____
the neural plate forms along the ______
weeks 1-3
midline of embryo
KNOW THIS
At weeks ________ : the neural plate forms along dorsal midline of embryo–Sinks into tissues to form neural groove with neural fold along each side
1-3
Development of the Nervous System: wks 2-3
Neural plate develops ___ after _____
Neural groove with Neural folds develops by ____
Neural crest is located ______
6 days, fertilization
18 days
dorsolaterally
Somites = primitive segments; a set of bilaterally paired blocks of paraxial mesoderm that form in the embryonic stage of development
New somites are formed in a _____ sequence.
At the end of the ____, 40 somites are present. Somites eventually form _____.
craniocaudal
4th week
muscle
Development of the Nervous System:
T/F - BOTH the CNS and the PNS arise from the ectoderm of the embyro
T! The ectoderm forms the skin + the nervous system, so this includes ANS and as well
Development of the Nervous System:** **wks 2-3
Neural plate
- By the end of _____ of embryonic life, the ectoderm has begun to thicken (caudally/dorsally/rostrally/ ventrally).
- This is the neural plate which shows a longitudinal groove along the middorsal line – the neural groove. The anterior end of the plate is much broader. This portion becomes the brain, while the narrower, caudal part forms the spinal cord.
day 19, dorsally
Development of the Nervous System:** **wks 2-3
Neural Plate
the Neural plate which shows a longitudinal groove along the _____. Which means the _____ also forms along the
The _____ end of the plate is much broader. This portion becomes ____, while the narrower, _____ part forms the _____.
middorsal line, neural groove.
anterior, the brain, caudal, spinal cord
Development of the Nervous System:** **wks 2-3
Neural plate–By the end of the 19th day of embryonic life, the ectoderm has begun to thicken dorsally. The neural plate which shows a longitudinal groove along the middorsal line – the neural groove. The anterior end of the plate is much broader. This portion becomes the brain, while the narrower, caudal part forms the spinal cord.
Neural groove–As the neural plate thickens and expands, its lateral edges are carried dorsally. These are the neural folds.
Neural folds–During the third week, the neural folds begin to meet and fuse along the middorsal line, forming the neural tube.
Neural tube–Neural tube remains open at both ends for a period of time, but by the end of the fourth week both ends close (rostral or anterior neuropore and the caudal or posterior neuropore
Development of the Nervous System:** **wks 2-3
Neural folds - During the _____ week, the neural folds begin to ____ along the middorsal line. Forming the ____
3rd week, meet and fuse
neural tube.
Development of the Nervous System:** **wks 2-3
The neural tube is formed at ____
3 weeks
Development of the Nervous System:** **wks 2-3
Neural tube
The neural tube remains open at both ends for a period of time, but by the ______both ends close. Applying directions to the portions of the tube that close, ______
end of the 4th week
(rostral or anterior neuropore + the caudal or posterior neuropore
Development of the Nervous System:** **wks 2-3
Neural crest = thinned lateral margins of the _____
- the neural crest forms a form a temporary intermediate layer between the ____ and the ____
- Divide in the ____, migrate laterally and become segmented in cell clusters between the ____ and ____
neural plate
neural tube, surface ectoderm
midline, neural tube, the somites
Development of Nervous system :wks 2-3
The neural crest gives rise to _____ (the precursors of neurons) which differentiate into three types of cells:
(1) afferent (sensory) neurons;
(2) postganglionic efferents neurons of the autonomic nervous system (ANS)
(3) adrenal medulla
neuroblast
Development of Nervous system:** **wks 2-3
Neural Ectoderm development:
The neural crest gives rise to neuroblasts (the precursors of neurons) which differentiate into three types of cells:
(1) _____
(2) _____
(3) _____
(1) afferent (sensory) neurons;
(2) POSTGANGLIONIC efferents neurons of the ANS
(3) adrenal medulla
Development of Nervous system:** **wks 2-3
Spongioblasts
spongioblasts are precursors of _____
Spongioblasts differentiate from the _____ and form several types of supporting cells (aka. neuroglia)-→ MAINLY capsule cells and Schwann cells
- neuroglia (supporting cells)*
- neural crest*
Schwann cells are located in the _____ nervous system.
another name for schwann cells is ____, amd they are responsible for laying down the _____of ____ nerves.
- peripheral*
- neurilemma* cells, myelin sheath, peripheral
Development of the Nervous System:** **wks 2-3
Neural crest gives rise to:
- ______ of the (ventral/dorsal) root ganglia of the spinal nerve
- Cranial nerves and ganglia
- Peripheral cells of the ANS
- Skin pigment, teeth
Primary sensory neurons, dorsal
Development of the Nervous System:** **wks 2-3
The following develop from with embryo structure?
- Primary sensory neurons of the DORSAL root ganglia of the spinal nerve
- Cranial nerves and their ganglia
- Peripheral cells of the ANS
- Skin pigment & teeth
neural crest
Development of the Nervous System:** **wks 2-3
At day _____, the Neural folds roll & fuse Begins in ____ - then zips ______. This process creates the _____
26
cervical region; zips caudally & rostrally, neural tube
Development of the Nervous System:** **wks 2-3
______ separates from ectoderm, sinks deeper, & grows processes that will form _____
Neural tube, motor nerve fibers
Development of the Nervous System:** **wks 2-3
At Day ___
The neural tube separates from the _____, sinks deeper, & grows processes that will form _____
26,
ectoderm, motor nerve fibers
Development of the Nervous System:** **wks 2-3
At Day ___ , ____ fills with fluid. This fluid will become _____ & _____
26, Neural tube, central canal of spinal cord & ventricles of brain
What is this?
This is Electron Microscopy of a neural tube forming. Remember that neuralation occurs caudally (starts at c/s and moves caudally)
Overview of the Development of the Nervous System:
the neural tube develops into the ____, ____, & ____
brain + spinal cord + ventricles (CSF)
Overview of the Development of the Nervous System:
The brain, spinal cord, and the ventricle (CSF) develop from the: ____
Neural tube
Overview of the Development of the Nervous System:
the brain, spinal cord, and ______ develop from the neural tube
ventricles (CSF)
Overview of the Development of the Nervous System:
the prosencephalon, mesencephalon, and rhombencephalon develop develop from _____
the neural tube
Overview of the Development of the Nervous System:
the neural tube develops into the: _____, ____, & ____
prosencephalon, mesencephalon, and rhombencephalon
Overview of the Development of the Nervous System:
the following develop from the _____
prosencephalon becomes the ____
the mesencephalon becomes the ____
the rhombencephalon becomes the _____
neural tube
pro = forebrain (includes telencephalon + diencephalon)
Mes = midbrain
rhomb = hindbrain (includes metencephalon + myelencephalon)
Overview of the Development of the Nervous System:
the telencephalon + diencephalon develop from the _____ which forms from the _____
proencephalon, neural tube
Overview of the Development of the Nervous System:
The midbrain tectum is _____ , and is formed from the _____
the roof of the midbrain, mesencephalon
Overview of the Development of the Nervous System:
The Midbrain tegmentum is ____ , and is formed from
midbrain tegmentum = floor of midbrain
mesencephalon
Overview of the Development of the Nervous System:
The Metencephalon is aka. _____ , and is formed from _____
after brain, rhombencephelon (which forms from the neural tube)
Overview of the Development of the Nervous System:
The Myelencephalon is aka. _____ , and is formed from _____
marrow brain, the rhombencephalon –→ neural tube
Overview of the Development of the Nervous System:
the pons & cerebellum form from the _____, which originates from development of the ______
metencephalon (after brain), neural tube
neural tube → rhombencephalon → metencephelon (after brain) → pons & cerebellum
→ myencephalon (marrow brain) → medulla
Overview of the Development of the Nervous System:
the medulla forms from the _____, which originates from development of the ______
Myelencephalon (marrow brain) , neural tube
neural tube → rhombencephalon → metencephelon (after brain) → pons & cerebellum
→ myencephalon (marrow brain) → medulla