Chapter 2-Merrill Flashcards
Historic Developments in Epidemiology
Hippocrates
1st recorded epidemiologist; attempted to explain disease occurrence using a rational basis rather than a supernatural basis; profound environmental influece associated with health
Hippocrates
Humors of the body; persisted for more than 200 years
Humors
Blood; phlegm; black bile; yellow bile
Hot humors
fever. caused by too much blood. lead to blood letting. treated with a cold treatment
Cold humors
treated with a hot treatment
atomic theory
everything is made of tiny particles
Galen
lifestyle and personality influences. elaborated on Hippocrates’ theory
Procatartic factors
the way a person lived (Galen)
Temperament factors
Innate qualities of the body leading to having too many or too few humors
Temperament factors
influenced health and disease; associated with a particular personality disease vulnerability but also with a particular personality type; lifestyle and personality can influence health and disease
Miasmas
General term for particles in the air; vapors
Hieronymous Fracastorius
Contagion
Contagion
Disease could be caused by particles too small to be seen and that these particles could be spread by close personal contact or from inanimate objects
Thomas Sydenham
Symptomology
Symptomology
Advocate for a strong empirical approach to medicine and close observation of disease. promoted the concept of diagnosis by symptomology (unconventional)
John Graunt
Father of modern demography (biostats)
John Graunt
noted that biological phenomenon (births and deaths) varied in predictable patterns
John Graunt
Contributed to the beginning of vital stats recordings (births, deaths, marriage, divorce)
James Lind
Scurvy
Scurvy
Deficiency in vitamin C. Results in abnormal bone formation and hemorrhage of the mucous membrane (diet on disease).
James Lind
noted for the first clinical trial in discovering a cure for survey
Noah Webster
Environmental influences of epidemics
Noah Webster
epidemics were related to certain environmental factors that combined to affect large populations at once
Noah Webster
studied yellow fever, scarlet fever, influenza
Edward Jenner
smallpox inoculation
Edward Jenner
noted link between cowpox and smallpox and was the first to inoculate
Edward Jenner
contribution was the basis of vaccination
Ignaz Semmelweis
hospital hygiene
Ignaz Semmelweis
noted link between sanitation and material mortality (cross infection). prevention (hygienic practices). contribution led the way for improving hospital hygiene
William Farr
father of modern vital stats and surveillance
William Farr
developed basic practices still used today including disease classification
William Farr
expanded mortality and morbidity analysis to include marital status, occupation, and attitude
William Farr
multifactorial etiology
Louis Pasteur
germ theory
Louis Pasteur
Rabies immunization
Louis Pasteur
demonstrated effective immunization against rabies, anthrax investigation/vaccine, pasteurization
PL Panum
natural history of measles
John Snow
Epidemiology of cholera
John Snow
father of modern epidemiology; spot dot mapping
John Snow
noted link between polluted water and cholera
John Snow
descriptive and analytical
Joseph Goldberger
epidemiology of pellagra
Joseph Goldberger
Deficiency of B-complex vitamin. Results in skin conditions, digestive problems, mental disturbances
Joseph Goldberger
developed the hypothesis that pellagra was not an infectious disease
Joseph Goldberger
nutritional epidemiology
Modern epidemiology
Since WWII, the discipline of epidemiology developed considerably in terms of research methods and outcomes
Doll & Hill
responsible for linking smoking to lung cancer
Framingham study
Conducted in Framingham, MA and was responsible for our understanding of the epidemiology of cardiovascular disease
Florence Nightengale
helped create changes in hygiene and overall treatment of patients
Mary Mallon/Typhoid Mary
chronic carrier of typhoid fever. 250 cases. no symptoms of disease
Typhoid Mary
taught the importance of: keeping track of carriers; food handles and regulation; health inspectors and quarantine