Chapter 2: image weighting and contrast Flashcards
intrinsic
cannot be changed
- body tissues
extrinsic
can be changed
- parameter settings
intrinsic contrast parameter
T1 recovery
T2 decay
Proton density
flow
apparent diffusion coefficient (ADC)
Extrinsic contrast parameter
TE
TR
Flip angle
Turbo factor/ echo train length
b value
thermodynamics
hydrogen nuclei will always seek its lowest energy state
- relaxation
T1 recovery
longitudinal plane
- spin lattice energy transfer
T2 decay
transverse plane
- spin-spin interactions
dephasing also caused by
inhomogeneities in the B0
Free induction decay
differences in processional frequency + dephasing + inhomogeneities
contrast w/ high signal
hyperintense
contrast w/ low signal
hypointense
higher proton density
more signal
T1 & T2 two factors
- molecular tumbling matches Larmor frequency
- molecules are packed close together
Fat
hydrogen + oxygen + carbon
- large molecules packed together
- slow tumbling rate
Water
2 hydrogen + oxygen
- molecules spaced far apart
- fast tumbling rate
tissues w/ high PD
large transverse magnetization- hyperintense
tissues w/ low PD
small transverse magnetization- hypointense
signal intensity depends on
- PD
-T1 recovery
-T2 decay
TR controls T1
visualizes anatomy
TE controls T2
visualizes pathology
PD- T1 & T2 is
dominated by PD to visualize anatomy and pathology
to minimize intrinsic contrast parameters
we select extrinsic parameters to dominate
to dominate T1, T2, PD weighting
we use TE or TR
Diffusion weighting
contrast is due to the differences in ADC between the tissues
apparent diffusion coefficient (ADC)
net displacement of molecules in an area of tissue per second
functional MRI
for brain activity
magnetic transfer contrast
suppresses background tissue and increases the CNR
susceptibility weighted imaging
uses susceptibility between tissues for contrast
contrast agents
gadolinium binded/ chelating with DTPA
short T1 & T2 relaxation time
fat
Long T1 & T2 decay time
water
Gauss
unit of magnetic flux for small changes in field strength
Tesla
unit of magnetic flux density for a large magnetic field
signal
voltage that is induced in the receiver coil
first few RF excitations pulses
preparatory
saturation when NMV is flipped
180 degrees
T1 weighted
short TE
short TR
T2 weighted
long TR
long TE