Chapter 2 - Homeostasis Flashcards
What does homeostasis do?
Ensures that the internal conditions of an organism are kept constant all the time
What is the importance of homeostasis?
A stable internal environment allows an organism to be independent of changes in the external environment
What are the internal conditions that should be kept constant?
Temperature pH Water potential Concentration of metabolic wastes Blood glucose concentration Carbon dioxide concentration
Why must temperature and pH level be kept constant?
Enzymes require an optimum temperature and pH to function properly
- Below the optimum temperature, enzymes are inactivated. Beyond the optimum temperature, enzymes are denatured
- Drastic changes in pH level in the blood affect the activity of enzymes and the rate of cellular reactions
How must water potential be kept constant?
The composition of tissue fluid has to be maintained
Why must water potential be kept constant?
Changes in the water potential affect the body cells
- Body cells will either shrink or burst in solutions with water potentials different from that in the cytoplasm
Why must blood glucose level be kept constant?
Glucose in food is required for tissue respiration which releases energy for cells to carry out their activities
- Glucose levels increase after a meal and decrease following physical exertion
- If blood glucose concentration changes drastically, it can be dangerous
What are the principles of homeostasis?
- A stimulus is a change from normal conditions in the internal environment
- Receptors detect stimulus
- A corrective mechanism brings about the reverse effect of the stimulus
- Negative feedback ‘tells’ the receptors that the condition has been restored back to normal state
What happens when a condition rises above normal?
Normal condition or set point → Stimulus (increases above norm) → Receptor (detects the stimulus) → Self-regulatory corrective mechanism → Condition decreases (+negative feedback to receptor) → Normal condition or set point
What happens when a condition decreases below normal?
Normal condition or set point → Stimulus (decreases above norm) → Receptor (detects the stimulus) → Self-regulatory corrective mechanism → Condition increases (+negative feedback to receptor) → Normal condition or set point
Regulating blood glucose concentration: excess glucose
- Stimulus: Concentration of blood glucose increases above the norm
- Receptor: Islets of Langerhans in pancreas stimulated
- Corrective Mechanism: Islets of Langerhans secretes more insulin, which is transported by blood to liver and muscles
- Permeability of cell surface membrane to glucose increases
- Liver and muscles convert excess glucose to glycogen. Glycogen is stored in liver and muscles.
- Concentration of blood glucose decreases and insulin production falls
- Concentration of blood glucose returns to normal
Regulating blood glucose concentration: insufficient glucose
- Stimulus: Concentration of blood glucose decreases above the norm
- Receptor: Islets of Langerhans in pancreas stimulated
- Corrective Mechanism: Islets of Langerhans secretes more glucagon, which is transported by blood to liver and muscles
- Glycogen stored in liver is converted to glucose
- Glucose is released into the bloodstream
- Concentration of blood glucose increases and glucagon production falls
- Concentration of blood glucose returns to normal
Regulating body water potential: too high
- Stimulus: Water potential of blood increases above the norm
- Receptor: Hypothalamus in brain detects stimulus
- Corrective Mechanism: Pituitary gland releases less ADH
- Less water is reabsorbed by kidney tubules
- More water is excreted and urine produced is more dilute
- Water potential of blood decreases
- Water potential of blood returns to normal
Regulating body water potential: too low
- Stimulus: Water potential of blood decreases below the norm
- Receptor: Hypothalamus in brain detects stimulus
- Corrective Mechanism: Pituitary gland releases more ADH
- More water is reabsorbed by kidney tubules
- Less water is excreted and urine produced is more concentrated
- Water potential of blood increases
- Water potential of blood returns to normal
Epidermis: Describe the cornified layer
- The outermost surface of the skin
- Consists of dead dry cells with keratin deposits
- Dead cells are continuously shed from skin surface
Epidermis: Describe the granular layer
- The middle layer of the epidermis
- Consists of living cells that move upwards
- Cells eventually become dry and dead to form cornified layer
Epidermis: Describe the Malpighian layer
- The innermost layer of the epidermis
- Consists of actively dividing cells that contain melanin