Chapter 2 - Chemical Messengers Flashcards
What are the two types of glands found in the body?
- Endocrine glands
- Exocrine Glands
How do Exocrine glands work?
Exocrine glands secrete into a duct that carries the secretion to the body surface or to one of the body cavities
What are four examples of Exocrine glands?
- Sweat glands
- Mucous glands
- Salivary glands
- Glands of the alimentary canal
How do Endocrine glands work?
Endocrine glands secrete hormones into the extracellular fluid that surrounds the cells that make up the gland - the secretion then usually passes into the capillaries to be transported by the blood
What are four examples of Endocrine glands?
- Hypothalamus
- Pituitary gland
- Thyroid gland
- Adrenal glands
What is a hormone?
A secretion of an endocrine gland
What may hormones be?
- Proteins
- Steroids
- Amines
What are amines?
Small molecules derived from amino acids
How are hormones transported?
They are transported throughout the body in the blood
What is a target cell?
A cell who’s activity is affected by a particular hormone
What is a target organ?
An organ who’s activity is affected by a particular hormone
What are paracrines? What is another name for paracrines?
Any chemical secreted by a cell that diffuses to and affects adjacent cells; also called a local hormone
What is saturation?
When all the receptor molecules are occupied by hormone molecules
What are hormone receptors?
Specific
What type of solublity are proteins/amines able for?
Water soluble - they cannot pass through the cell membrane (facilitated diffusion)
What type of solubility are steroids able for?
Lipid soluble - can easily pass through the cell membrane into the cytoplasm (diffusion)
What do proteins/amines bind to?
Receptor molecules on the cell membrane (extracellular fluid) - does not enter the cell membrane
What do steroids bind to?
Receptor proteins inside the cell, then binds to a recptor on the nucleus to form an active receptor complex
When amine hormones bind to a receptor, what is produced?
A secondary message response
What does the secondary message response do?
This response will activate particular enzymes in the cell
What occurs when steroids bind to receptors in the nucleus?
Enzymes are activated in the nucleus - particular genes will be able to form a particular protein
At what speed do amines/proteins act?
Fast acting - the effect occurs in seconds or minutes
At what speed do steroids act?
Slow acting - the effect occurs in hours or days
What are some examples of protein based hormones?
- Insulin
- The growth hormone
- Adrenaline