Chapter 2 - Chemical Messengers Flashcards
exocrine glands
π secrete into duct
π duct carries secretion to body surface/body cavities
πsweat glands
πmucous glands
πsalivary glands
πglands of alimentary canal
endocrine glands
π secrete hormones
π secrete them into extracellular fluid of cell that makes up gland
β« secretion then passes into capillaries/bloodstream
The Endocrine Glands
π hypothalamus π pituitary π pineal π thyroid π parathyroid π thymus π adrenal glands π pancreas π gonads
Hormones
π secretion of an endocrine gland
π proteins and amines
π steroid
π transported in blood
π can affect all cells of body or specific cells (target cells)/organs (target organs)
paracrines
π local hormones
π diffuse from cells to adjacent cells
π move through extracellular fluid (not bloodstream)
π for cells to communicate with other cells
protein and amine hormones
π attach to receptor proteins in MEMBRANE of target cell
π receptor proteins
βοΈ are specific
βοΈ only a certain amount
βοΈ different cells have different types and amounts
π hormone β receptor β‘οΈ secondary messenger substance
secondary messenger substance βοΈ diffuses through cell βοΈ activates particular enzymes
steroid hormones
π combine with receptor protein INSIDE CELL
(mitochondria, nucleus, other organelles)
hormone-receptor complex βοΈ activates genes βοΈ the genes control forming of particular protein
Hormones canβ¦
1οΈβ£ activate certain genes in nucleus
2οΈβ£ change shape of enzyme (so itβs turned ON or OFF)
3οΈβ£ change rate of production of an enzyme
β done by changing rate of transcription/translation
enzyme amplification
π production of thousands of enzymes via bondage of hormone to receptor
hormone triggers cascading effect
β‘οΈ no. of molecules involved increases x1000s for each step along metabolic pathway
π small stimulus = very large effect
hormone clearance
1οΈβ£ hormone molecules broken down
βοΈ in liver/kidneys βοΈ some in target cells
2οΈβ£ degraded hormones secreted
βοΈ bile βοΈ urine
Negative feedback system
π control of hormone secretions
βοΈ regulates hormone secretions
βοΈ response produced
β‘οΈ opposite of stimulus that caused the secretion
βοΈ regulating factors from hypothalamus
β‘οΈ regulate function of pituitary
βοΈ releasing factors from hypothalamus
β‘οΈ stimulate release of a hormone OR inhibiting factors
Hypothalamus
π regulating and maintaining internal environment
βοΈ body temperature βοΈ water balance βοΈ heart rate
π located at the base of the brain
Pituitary gland
π absolutely vital to internal functioning of body
π anterior and posterior lobe
π underneath and connected to hypothalamus
β‘οΈ infundibulum
Anterior lobe of pituitary
π releases hormones that regulate bodily activities
π secretions controlled by releasing/inhibiting factors from hypothalamus
(extracellular fluid -> bloodstream)
π connected to hypothalamus by complex network of blood vessels
π FLATPEG
Hormones released by anterior lobe
π FHS π LH π ACTH (adrenocorticotropic hormone) π TSH π Prolactin π Endorphins* π Growth hormone (GH)