Chapter 2 - Cell Physiology Flashcards
0
Q
Passive forces
A
- forces that do not require the cell to expend energy to produce movement
1
Q
Selectively permeable
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- characteristic of the plasma membrane - permits some particles to pass through, while excluding others
2
Q
Active forces
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- forces that do require the cell to expend energy (ATP) to transport a substance across the membrane
3
Q
Diffusion
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-
4
Q
Concentration gradient
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- a difference in concentration between two adjacent areas
5
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Net diffusion
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- the difference between two opposing movements
6
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Steady state
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- movement of molecules from area A to area B that is exactly matched by the movement of molecules from area B to area A
7
Q
Fick’s law of diffusion
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- factors contributing to the rate of net diffusion across the membrane
8
Q
Electrical gradient
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- a difference in charge between two adjacent areas that promotes the movement of ions towards the area of opposite charge
9
Q
Electrochemical gradient
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- when both an electrical and a concentration gradient act simultaneously on a specific ion
10
Q
Aquaporins
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- channels used for the passage of water - formed by membrane proteins - allow about a billion water molecules can pass single file through this channel in one second
11
Q
Osmosis
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- net movement of water across a membrane down its concentration gradient - passive
12
Q
Hydrostatic pressure
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- the pressure exerted by a stationary fluid on an object (the plasma membrane)
13
Q
Osmotic pressure
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- a measure of the tendency for water to move into that solution because of its relative concentration of nonpenetrating solute sand water
14
Q
Tonicity
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- the effect the solution has on cell volume when the solution surrounds the cell
15
Q
Isotonic solution
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- a solution with the same concentration of nonpenetrating solutes as normal body cells do
16
Q
Hypotonic solution
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- a dilute solution - a solution with a below normal concentration of nonpenetrating solutes - causes RBCs to swell
17
Q
Hypertonic solution
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- a concentrated solution - a solution w an above normal concentration of nonpenetrating solutes - the cells shrink as they lose water by osmosis
18
Q
Transport maximum
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- the limit to the amount of a substance a carrier can transport across the membrane in a give time - related to carrier-mediated transport
19
Q
Carrier-mediated transport
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- a molecule to be transported attaches to a binding site within the interior of the carrier on one side of the membrane - binding causes the carrier to flip its shape so that the same site is now exposed to the other side of the membrane - the bound molecule detaches from the carrier - the carrier reverts to its original shape
20
Q
Active transport
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- requires the carrier to expend energy to transfer its passenger uphill against a concentration gradient, from an area of lower concentration to an area of higher concentration - used to transport specific ions or polar molecule
21
Q
Hydrogen ion H+ pumps
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- an example of the simple active transport - used by specialized stomach cells to transport H+ into the stomach lumen in association w he secretion of HCl during digestion of a meal - moves H+ against a tremendous gradient
22
Q
Na+/K+ ATPase pump
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- involves the transfer of three sodium ions out of the cell and two potassium ions in - an example of active transport
23
Q
Cotransport carriers
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- an example of secondary active transport - example: luminal carriers in intestinal and kidney cells - two binding sites, one for Na+ and one for the nutrient molecule
24
Q
Secondary active transport
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- Active transport - moves molecules against the concentration gradient - driven by ion gradient established by ATP requiring primary pump
25
Q
Ion concentration gradient
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-
26
Q
Vesicular transport
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- transfers large particles between the ECF and the ICF by wrapping contents in membrane enclosed vesicles - requires energy expenditures by the cell - active method of transport
27
Q
Pinocytosis
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- brings a small droplet of ECF into the cell - form of active, vesicular transport - plasma membrane dips inwards and pinches off at surface, forming an internalized vesicle
28
Q
Receptor mediated endocytosis
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- used to transport specific large polar molecule - active, vesicular transport - plasma membrane dips inwards and pinches off at the surface, forming an internalized vesicle
29
Q
Phagocytosis
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- used to transport multimolecular particles (bacteria and cellular debris) - active form of vesicular transport - cell extends pseudopods that surround particle, forming an internalized vesicle