Chapter 2 and 7 - Anatomy of the NS Flashcards

1
Q

Neuron

A

The basic functional unit of the nervous system

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2
Q

Nerve

A

A bundle of axons in the peripheral nervous system

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3
Q

Tract

A

A bundle of axons in the central nervous system

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4
Q

Ganglion

A

A group of cell bodies in the peripheral nervous system

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5
Q

Nucleus

A

A group of cell bodies in the central nervous system

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6
Q

Neuroanatomical Directions

A

Brain:
Dorsal - up
Ventral - down
Anterior - front
Posterior - back

Spine:
Anterior - up
Posterior - down
Ventral - front
Dorsal - back

Others:
Medial – towards the middle
Lateral – towards the side
Proximal – close to the body
Distal – further away from body
Contralateral – opposite side
Ipsilateral – same side

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7
Q

Sections of the Brain

A

Horizontal – a slice parallel to the ground

Frontal (coronal) – slicing bread or salami

Sagittal – a midsagittal section separates the left and right halves

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8
Q

2 Parts of the Nervous System

A

Central nervous system

Peripheral nervous system

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9
Q

Anatomy - Central Nervous System (CNS)

A

Brain (in the skull)

Spinal Cord (in the spine)

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10
Q

Anatomy - Peripheral Nervous System (PNS)

A

Located outside of the skull and spine

Serves to bring information into the
CNS and carry signals out of the CNS

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11
Q

The CNS is covered by…

A

three meninges and encased in bone (skull or spinal cord)

  1. Dura mater - tough outer membrane
  2. Arachnoid membrane - weblike
  3. Pia mater - adheres to CNS surface

Cerebrospinal fluid (CSF)
- Fluid serves as cushion

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12
Q

Cerebrospinal Fluid

A

Acts as cushion for CNS

Found in:
1. Subarachnoid space → between arachnoid membrane and pia mater

  1. Ventricles → Series of hollow interconnected chambers, filled with CSF
  • 4 ventricles: 2 lateral, 3rd and 4th
  • Cerebral aqueduct
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13
Q

2 Parts of the Peripheral Nervous System

A
  1. Somatic Nervous System:
  • interacts with external environment
    (Afferent nerves (sensory to CNS))
    (Efferent nerves (motor from CNS))
  • info from sense organs to CNS
  • voluntary muscles control
  1. Autonomic Nervous System
  • regulates body’s internal environment
    (Afferent nerves (sensory from internal organs to CNS))
    (Efferent nerves – 2 kinds)
  • controls heart, intestines, etc
  • involuntary muscles
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14
Q

Autonomic Nervous System

A

Sympathetic and parasympathetic nerves generally have opposite effects

Sympathetic - fight or flight

Parasympathetic - rest and relaxation

Both outputs we don’t control

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15
Q

Cranial Nerves

A

I - Olfactory nerve - olfactory

II - Optic - vision

III - Oculomotor - eye movements, control of pupil, lens and tears

IV - Trochlear - eye movements

V - Trigeminal - facial sensations, chewing

VI - Abducens - eye movements

VII - Facial - facial movements, salivary glands, taste

VIII - Vestibulo-cochlear nerve - acoustic branch, vestibular branch

IX - Glossopharyngeal - throat muscles, salivary glands, taste

X - Vagus - control and sensation of internal thoracic and abdominal viscera such as bronchioles, heart and stomach

XI - Spinal accessory - head and neck muscles

XII - Hypoglossal - tongue muscles

“on old Olympus’s towering top a Finn and German viewed some hops”

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16
Q

Development of the Human Brain

A

From the ectoderm of our embryotic cells, we develop a neural tube

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17
Q

The 5 Major Divisions of the Human Brain

A
  1. Telencephalon
  2. Diencephalon
  3. Mesencephalon
  4. Metencephalon
  5. Myencephalon
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18
Q

Major Divisions of the Brain, Continued

A

Forebrain - Telencephalon, Diencephalon

Midbrain - Mesencephalon

Hindbrain - Metencephalon, Myelencephalon

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19
Q

Hindbrain Divisions - Myelencephalon

A

Medulla
- life support functions
- damage

Reticular formation
- gate keeper, can admit or block sensory info
- many general anesthetics work here
- damage

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20
Q

Hindbrain Divisions - Metencephalon

A

Pons
- bridge
- ventral surface
- main connection b/w cortex and cerebellum
- role in sleep, dreaming, eye movements, vestibular sense

Cerebellum
- little brain

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21
Q

Midbrain Divisions - Mesencephalon

A

Tectum - dorsal surface

Tegmentum - ventral

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22
Q

Tectum

A

“Roof”

Superior colliculus - vision

Inferior colliculus - audition

Visual reflexes and reactions to moving stimuli

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23
Q

Tegmentum

A

3 colourful structures:

Periaqueductal gray - analgesia
Substantia nigra - sensorimotor
Red nucleus - sensorimotor

24
Q

Forebrain Divisions - Diencephalon

A

Thalamus

Hypothalamus

25
Q

Thalamus

A

Switchboard

Senses (except olfaction) stop here before going to appropriate area of cortex

LGN - vision

MGN - audition

VPN – touch, taste

26
Q

Hypothalamus

A

Located just below thalamus

Homeostatic control motivated behaviors

HOW?
Through the release of hormones from pituitary gland
(dangles beneath hypothalamus)

27
Q

Cerebral Cortex

A

Surrounds the cerebral hemispheres, convolutions serve to increase surface area

Made up of:
- sulci (small grooves)
- fissures (large grooves)
- gyri (bulges or bumps)

Longitudinal fissure –
a groove that separates right and left hemispheres

28
Q

Major Fissures of Cerebral Hemispheres

A

Lateral fissure

Central fissure

Longitudinal fissure

29
Q

Lobes of the Brain

A

Frontal lobe

Central sulcus

Parietal lobe

Occipital lobe

Sylvian fissure

Temporal lobe

Cerebellum

30
Q

Broadman Areas

A

Defined by their cytoarchitecture
- structure of their cells

31
Q

Neurons

A

Functional unit of the NS

Specialized for the reception, conduction and transmission of electrochemical signals

Many sizes and shapes

32
Q

External Anatomy of a Neuron

A

Cell membrane
Dendrites
Axon hillock
Axon
Myelin
Nodes of Ranvier
Cell body
Buttons
Synapses

33
Q

Cell Membrane

A

The semipermeable membrane that encloses the neuron

34
Q

Dendrites

A

The short process emanating from the cell body, which receives most of the synaptic contacts from other neurons

35
Q

Axon Hillock

A

The cone-shaped region at the junction between the axon and the cell body

36
Q

Axon

A

The long, narrow process that projects from the cell body

37
Q

Cell Body

A

The metabolic center of the neuron, also called the SOMA

38
Q

Myelin

A

The fatty insulation around many axons

39
Q

Nodes of Ranvier

A

The gaps between sections of myelin

40
Q

Bottons

A

The buttonlike endings of the axon branches, which release chemicals into synapses

41
Q

Synapses

A

The gaps between adjacent neurons across which chemical signals are transmitted

42
Q

The Antenae of the Neuron

A

Dendrites - collect incoming signals from other neurons

Incoming signals are comboined and processed; if strong enough, they are passed forward through the soma

43
Q

Dendritic Morphology (shape)

A

Neurons can be classified by the nature of their dendrites

Dendritic branching
Dendritic spines

44
Q

Parts of the Neural Soma (cell body)

A

Cytoplasm
Gogli apparatus
Membrane
Mitochondria
Myelin sheath
Microtubules
Lysosome
Dendritic spines
Smooth endoplasmic reticulum
Rough endoplasmic reticulum
Dendrite

45
Q

DNA Expression

A

DNA ➡️ RNA ➡️ Protein

Replication (DNA duplicates) ➡️ Transcription (RNA synthesis) ➡️
Translation (protein synthesis)

46
Q

Regulating DNA Expression

A

Promoters - sequence of DNA that increases the likelihood of genetic expression

Transcription Factors - protiens that regulate the polymerase

Stop Sequence - sequence of DNA that stops transcription

47
Q

Axon Collaterals

A

Parallel (branching) paths that the axon from a single neuron may take

47
Q

Axon Transport

A

Some material needed at the end of the axon are too big to be built there

They are built in the cell body and transported
(the transport protein is KINESIN)

Axoplasmic Transport - occurs from the soma to the button

48
Q

At The Button - Synapse

A

The junction between the axon buttons/terminal of one sell, and the body/dendrites of another is called SYNAPSE

49
Q

What happens at the axon terminal?

A

Exocytosis

50
Q

The Support Structures of the Neuron

A

Microtubules

Neurofilament

Microfilaments

51
Q

Microtubules

A

Long pipes running down the axon

Regulated by “microtubule associated proteins”

52
Q

Neurofilament

A

Consists of wound rope-like subunits

Very strong

53
Q

Microfilaments

A

Most densely found in the “neurites”

Plays a role in changing shapes of a sell (actin)

54
Q

Glial Cells

A

Support and nourish neurons

Recent evidence for glial communication and modulatory effects of glia on neuronal communication

55
Q

4 Classes of Glial Cells

A

Oligodendrocytes:

  • extensions rich in myelin create myelin sheaths in CNS

Schwann Cells:

  • similar to function of oligodendrocytes but in PNS, csn guide axonal regeneration

Astrocytes:

  • large glia, start-shaped, many functions

Microglia:

  • involved in response to injury or disease