CHAPTER 2 Flashcards
During replication, the DNA synthesis can only make one direction which is 3’ to 5’ direction
False
DNA replication results in 2 DNA molecules, 1 with two new strands and the other with two original strands
False
The DNA under the control of the origin of replication i
Replicon
DNA replication is carried out in all organisms by a multiprotein complex called
Replisome
It is a type of DNA damage, that has a cross-links adjacent pyrimidine on the same DNA strand, forming 2 major lesions, the vast majority of the lesions are pyrimidine dimers in which the 2 carbons on each of the two pyrimidine form a cyclobutyl ring
UV Radiation
The replication forks move bidirectionally, and they keep moving until they reach the end of the chromosome, which is known as
Telomere
If an alpha catalytic subunits continues to synthesize in a short stretch of DNA before the DNA polymerase takes over the replucation process, this will be called as
Polymerase Switching
In a base excision repair, a base that has been damaged by oxidation or chemical modification can be recognized by
DNA glycosylase
Complementary strand for the DNA sequence 5’-GATCCTGAAC-3’
3’-CTAGGACTTG-5’
During the replication process, what variety of DNA hypothesis does the DNA replication mechanism occurs?
Semiconservative model
Valid on the process of DNA replication
DNA gyrase and helicase work to unwind the DNA so that it can be replicated
In the process of DNA replication, both replication forks will travel in the same direction and helicase will work to unwind the DNA, allowing the synthesis of new strands to occur
False
A _ is a sequence involved in termination, that contains a short 23-bp sequence
Ter site
An enzyme that can only add to nucleotides to the 3’ end of a nucleotide fragment?
DNA polymerase
An enzyme that harness the chemical energy for the ATP hydrolysis to separate the 2 DNA strands at the replication fork
Helicase
