Chapter 2 Flashcards
The Animal Welfare Act is administered by what agency?
USDA Animal and Plant Health Inspection Service
What is the common test for the policy that most institutions have to protect an individual reporting instances of animal abuse or neglect?
Whistleblower policy
Name the person to whom the IACUC is responsible.
Institutional Official
What regulations were developed by the Food and Drug Administration (FDA) and the Environmental Protections Agency (EPA) to validate and document the process of safety testing?
Good Laboratory Practices (GLP’s)
What agency is responsible for enforcing the Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS Policy) ?
Office of Laboratory Animal Welfare (OLAW)
What document must be submitted to the USDA every year by an animal facility with USDA-covered species?
An annual report
The PHS Policy on Humane Care and Use of Laboratory Animals applies specifically to what type of research?
Federally funded research
If research is funded by agencies of the PHS, what document must the Institutional Official send to OLAW about the institution’s animal care and use program?
Animal Welfare Assurance of Compliance Statement or PHS Assurance
T/F: Mice bred for research are not covered by the Animal Welfare Act.
True
Upon request, USDA records are available to the public under what federal act?
Freedom of Information Act
What IACUC approved document must a PI submit describing/justifying the use of animals for each research project involving lab animals?
Animal use protocol or Animal protocol
T/F: The Animal Welfare Regulations is another name for the Animal Welfare Act.
False. The Animal Welfare Regulations describe what rules a facility must follow to comply with the AWA.
What committee oversees the institution’s animal research programs?
IACUC (Institutional Animal Care and Use Committee)
Name the 3 R’s Principles of Russell & Burch.
Refinement, Reduction, Replacement
What is the federal mandate that covers all live vertebrates used in research?
PHS Policy
What are written instructions approved by management and used to perform a routine activity called?
SOP’s (Standard Operating Procedures)
What two government agencies developed Good Laboratory Practices?
EPA and FDA
What three types of members must make up IACUC?
The Chair (A scientist in Lab Animal Research) A veterinarian A non-affiliated member (no connection to animal research industry)
What are some components of an animal care and use program for which the Guide describes standards?
Personnel qualifications and training Occupational health and safety Veterinary care Animal environment Animal procurement and transportation Surgical and post-surgical care Alleviation of pain and distress Euthanasia Plant design and construction
What document must institutions comply with when euthanizing?
AVMA Guidelines for Euthanasia
Common alternatives to using animals?
Cellular cultures
Mathematical models
