Chapter 2 Flashcards
What distinguishes neuropsychological assessment from psychological assessment?
Neuropsychological assessment lies in a conceptual frame of reference that takes brain function as its point of departure
Which early instruments for studying the brain function are still in use?
Electrophysiological instruments such as: EEG, EP, ERP
EEG is especially useful in…..
Diagnosing seizure disorders and sleep disturbances, and for monitoring depth of anesthesia
Both EP and ERP…
Can identify hemispheric specialization and assess processing speed and efficiency
Resolution of EEG and MEG
They have both high temporal resolution but neither technique has good spatial resolution
How is electrodermal activity measured and what reflects it?
Electrodermal activity is measured by skin conductance response (SCR) and reflects autonomic nervous system functioning and provides a sensitive and very robust measure of emotional responses and feelings
Electrodermal activity and other autonomic measures such as heart rate, respiration, and pupil dilation have also been used to …
To demonstrate various nonconscious forms as brain processing (example: prosopagnosia)
What snares neuropsychological assessment with psychological assessment?
It relies on many of the same techniques, assumptions, and theories, along with many of the same tests
What reflects Regional cerebral blood flow (rCBF)?
The brain’s metabolic activity indirectly as it changes the magnitude of blood flow in different brain regions
When is it best to use CT and when MRI?
A CT might be best suited for acute head injury when skull fracture and/or bleeding are suspected
MRI (with diffusion tensor imaging) might be the study of choice in the chronic stages of head injury, when the clinician is especially concerned about white matter integrity
PET / SPECT
PET visualizes brain metabolism directly as glucose radioisotopes emit decay signals , their quantity indicating the level of brain activity in a given area
SPECT is similar to PET but less expensive and involves a contrast agent that is readily available
How can you identify the site of seizure onset?
Make a comparison of interictal and ictal SPECT scans
One important clinical application for PET is:
The diagnosis of neurodegenerative diseases.
Many neurodegenerative diseases produce brain alterations that are detectable with PET even when structural neuroimaging fails the show specific abnormalities
How does fMRI works?
Increasing neural activity requires more oxygen: the amount of oxygen delivered by the blood flow actually tends to exceed demand, creating a ratio of oxygenated to deoxygenated blood that is known as the BOLD signal. This signal is highly localizable
Why is fMRI popular in research?
- superior spatial resolution
- fMRI is widely available
- noninvasive
- does not require a medical context for its application