Chapter 2 Flashcards
Define aging
The process of growing older that begins at birth
What are nonstochastic theories?
Explain biological aging as resulting from a complex, predetermined process
What are stochastic theories?
View the effects of biological aging as resulting from random assaults from both the internal and external environment
What is the main premise of the cross-linking theory?
Cellular division is threatened as a result of radiation or chemical reaction, creating cross-linking agents
What do free radicals and lipofuscin theories focus on?
Oxidative metabolism and effects of free radicals; lipofuscin accumulation interferes with normal processes
What does the wear and tear theory suggest?
Repetitive use, injury, and stress result in breakdown of the body
What is the mutation accumulation theory?
Declining force of natural selection with age
What does the antagonistic pleiotropy theory propose?
Accumulated mutant genes that have negative effects in late life may have beneficial effects in early life
What is the disposable soma theory?
Aging is related to the use of the body’s energy rather than genetics
What is programmed cell death in the context of aging?
Continuous occurrence of cell death throughout life due to biochemical events
What does the genetic theory of aging suggest?
Born with a genetic program that predetermines life span
What is the error theory in aging?
Genetic mutations cause organ decline as a result of self-perpetuating cellular mutations
What do autoimmune reactions refer to in aging?
Changes in immune function with aging
What are neuroendocrine and neurochemical theories focused on?
Changes in brain and endocrine glands with aging
What do nutrition theories suggest about aging?
Good diet may minimize or eliminate some ill effects of aging