chapter 2 Flashcards
what is differentiation?
the generation of specialized cell types
what is commitment?
process where the developmental fate of a cell has restricted
what is specification?
cells will differentiate autonomously in a neutral environment but still labile (cound change depending on environment)
what is determination?
cells will differentiate autonomously and is not labile
what are the levels of commitment in cells?
unspecified-specifies-determined-differentiation
what is autonomous specification?
gives rise to a pattern of embryogenesis called mosaid development
what gene regulates muscle development in the tunicate?
the macho gene
what is conditional specification?
cells achieve their respective fates by interacting with other cells
what did weissman predict?
germ plast theory
what is the germ plast theory?
sperm and egg provide equal contributions to embryo, chromosomes carry inherited potential, only sex cells inherited all determinants
who was the first person to test weissmans predictions?
wilhem roux, on early frog embryos
what was the result of roux’s defect?
supported mosaic development, in the 2-cell stage one half was injected with a hot needle that killed the cell, when the cell reached blastula stage, half of it had dead tissue which resulted a destroyed half of an embryo