Chapter 19 (Patterns of Chromosome Inheritance) Flashcards

1
Q

What is a chromosome?

A

The genetic material is arranged into chromosomes, structures that assist in the transmission of genetic information from one generation to the next

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2
Q

What is the difference between chromosome and chromatin?

A
  1. untangles and unfolded DNA that exists as a complex while chromosomes contain the highest condenses structure of the DNA double helix for proper separation.
  2. Chromosomes are only found during cell division, where as chromatin is found throughout inter phase.
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3
Q

What is a karyotype?

A

A karyotype is used to visualize the chromosomes of a cell

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4
Q

Know the term for the genetically-identical chromosomal units, produced during replication, and attached at the centromere:

A

Sister chromatids; these chromosomes are said to be replicated or duplicated chromosomes because the two sister chromatids contain the same genes.

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5
Q

Define the term centromere:

A

A centromere holds the chromatids together until a certain phase of mitosis, when the centromere splits.

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6
Q

What are the parts of the cell cycle?

A

Interphase: G1 stage, S stage, G2 stage

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7
Q

What is interphase?

A

in this time organelles in the cell carry on their usual functions. As the cell continues through interphase, it gets ready to divide. The cell grows larger, the number of organelles doubles, and the amount of chromatin doubles as DNA replication occurs.

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8
Q

What happens during the G1 stage?

A

the cell returns to normal size and resumes its function in the body. A cell doubles its organelles and it accumulated the material needed for DNA synthesis. (GROWTH)

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9
Q

What happens during the S stage?

A

a copy is made of all DNA in the cell. DNA replication occurs, so each chromosome consists of two identical DNA double-helix molecules. These molecules occur in the strands called sister chromatids. (GROWTH & DNA REPLICATION)

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10
Q

What happens during the G2 stage?

A

the cell synthesizes the proteins needed for cell division, such as the proteins found in microtubules. (GROWTH AND FINAL PREPARATION FOR DIVISION)

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11
Q

What is mitosis?

A

A type of cell division that results in two daughter cells each having the same number and kind of chromosomes as the parent nucleus, typical of ordinary tissue growth

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12
Q

What is cytokinesis?

A

The cytoplasmic division of a cell at the end of mitosis or meiosis, bringing about the separation into two daughter cells.

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13
Q

What are the stages of mitosis?

A

Prophase, Prometaphase, Metaphase, Anaphase and Telophase

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14
Q

What happens during Prophase?

A

chromatin condenses into chromosomes, and the nuclear envelope, or membrane, breaks down.

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15
Q

What happens during Prometaphase?

A

the spindle fibers attach to the centromeres as the chromosomes continue to shorten and thicken. During prometaphase, chromosomes are randomly placed in the nucleus.

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16
Q

What happens during metaphase?

A

the cell’s chromosomes align themselves in the middle of the cell through a type of cellular “tug of war.” The chromosomes, which have been replicated and remain joined at a central point called the centromere, are called sister chromatids.

17
Q

What happens during anaphase?

A

begins when the duplicated centromeres of each pair of sister chromatids separate, and the now-daughter chromosomes begin moving toward opposite poles of the cell due to the action of the spindle.

18
Q

What happens during telophase?

A

the sister chromatids reach opposite poles. The small nuclear vesicles in the cell begin to reform around the group of chromosomes at each end.

19
Q

What happens at the G1 checkpoint?

A

cell cycle main checkpoint. If DNA is damaged, apoptosis will occur. Otherwise, the cell is committed to divide when growth signals are present and nutrients are available

20
Q

What happens at the G2 checkpoint?

A

mitosis checkpoint. Mitosis will occur if DNA has replicated properly. Apoptosis will occur if the DNA is damaged and cannot be repaired.

21
Q

What happens at the M checkpoint?

A

spindle assembly checkpoint. Mitosis will not continue if chromosomes are not properly aligned.

22
Q

What is apoptosis?

A

The death of cells which occurs as a normal and controlled part of an organism’s growth or development.

23
Q

What is signal transduction?

A

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.

24
Q

Difference between parent cells and daughter cells.

A

Mitosis is the process a single cell uses to divide into two new identical cells. The original cell is called a parent cell, and the newly formed cells are referred to as daughter cells. This replication process assures that newly created daughter cells will each have the same DNA as the original parent cell.

25
Q

How many daughter cells are made from each parent cell during mitosis?

A

Mitosis creates two identical daughter cells that each contain the same number of chromosomes as their parent cell.

26
Q

Define the term mitotic spindle?

A

The mitotic spindle is the macromolecular machine that segregates chromosomes into two daughter cells during mitosis.

27
Q

Know which types of cells undergo mitosis and which undergo meiosis.

A

Whereas sexual reproductive cells (sperm, eggs, spores) undergo meiosis. Mitosis is when a cell divides to produce an identical copy of itself and is how we grow and replace old cells. Meiosis is when one diploid cell undergoes two divisions to form 4 haploid reproductive cells.

28
Q

Describe the difference between the number of chromosomes in a diploid cell and haploid cell

A

Diploid cells contain two complete sets (2n) of chromosomes. Haploid cells have half the number of chromosomes (n) as diploid.

29
Q

What is interkinesis?

A

Interkinesis or interphase II is a period of rest that cells of some species enter during meiosis, between meiosis I and meiosis II. No DNA replication occurs during interkinesis, however it does occur during the interphase I stage of meiosis

30
Q

Define monosomy.

A

Monosomy is a form of aneuploidy with the presence of only one chromosome from a pair. Partial monosomy occurs when a portion of one chromosome in a pair is missing.

31
Q

Define Trisomy.

A

A trisomy is a type of polysomy in which there are three instances of a particular chromosome instead of the normal two. A trisomy is a type of aneuploidy (an abnormal number of chromosomes).