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Chapter 19 Flashcards

1
Q

Variations in size

A

Anisocytosis

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2
Q

Parameter that measures single cell size

A

Mean Cell Volume (MCV)

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3
Q

Parameter that measures variations in cell size

A

RBS distribution width (RDW)

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4
Q

Parameters used to identify the presence of anisocytosis

A

RDW & MCV

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5
Q

RBC that is less than 6 micrometer

A

Microcytic

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6
Q

Rbc that is greater than 8 micrometer

A

Macrocytic

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7
Q

Rbc that ranges from 6-8 micrometer

A

Normocytic

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8
Q

Disease associated with microcytic

A 
SITA 
Sideroblastic 
Iron deficiency 
Thalassemja 
Anemia of chronic dse
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9
Q

Disease associated with macrocytic

A 
VFMAC 
Vit B12 def
Folate def 
Megaloblastic anemia
Aplastic 
Chronic liver dse
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10
Q

Disease associated with normocytic

A

AHA
Acute post hemorrhagic anemia
Hemolytic anemia
Aplastic anemia

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11
Q

Microystis is due to?

A

Decreased hgb synthesis

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12
Q

Alteration in color

A

Anisochromia

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13
Q

It is the result of a defect in either nuclear maturation or stimulated erythropoiesis

A

Macrocystis

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14
Q

What are the three types of anisochromia

A

Hypochromia, normochromic, polychromatophilia

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15
Q

Disease assoc with normochromic

A

AHA

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16
Q

This stage of RBC maturation exhibits polychromatophilia

A

Polychromatophilic erythrocyte (Reticulocyte)

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17
Q

It has large, pale overall appearance and large central palloa

A

Hyprochromia

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18
Q

Disease associated with hypochromia

A

TIA
Thalassemia
Iron def anemia
Acute blood loss

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19
Q

General term for cells with different shape

A

Poikilocytes

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20
Q

Will you pas this sem?

A

Absolutely indeed

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21
Q

Variation in shape

A

Poikilocytosis

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22
Q

Poikilocyte that is evenly spaced pointed projection

With central pallor

A

Echinocyte

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23
Q

Other name for echinocyte

A

Burr cell

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24
Q

Other name for acanthocyte

A

Spurr cell

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25
Q

Poikilocyte that is small and round. Sphere shape

A

Spherocyte

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26
Q

Disease associated with Burr cell

A

PUG
Pyruvate kinase def
Uremia
Gastric carcinoma

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27
Q

Artifact in drying smear

A

Burr cell

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28
Q

Irregulary spaced projections

With no central pallow

A

Acanthocyte (spur cell)

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29
Q

Associated diseases of acanthocyte

A 
HACS 
Hemolytic
Abetalipoproteinemia 
Cirrhosis 
Splenectomy
30
Q

Disease associated with spherocyte

A 
HBHD 
Hereditary spherocytosis 
Burns 
Hemolytic 
Disseminated intravascular coagulation
31
Q

These are group of fragmented erythrocytes

A

Schistocyte

32
Q

3 types of schistocyte

A

Schizocyte
Bite cells /keratocyte / helmet cell
Blister cell

33
Q

Associated diseases with schistocyte

A

MSR
Microangiopathic hemolytic anemia
Severe burns
Renal graft rejection

34
Q

Poikilocyte result of splenic pitting of heinz bodies

A

Bite and blister cells

35
Q

Also known as target cell

36
Q

Has one blunt projection

A

Dacryocyte

37
Q

Central concentration of hemoglobin surrounded by colorless area with peripheral ring of hemoglobin

A 
TAHOP 
Thalassemia 
Artifact 
Hemoglobinopathies 
Obstructive liver disease 
Post splenectomy
38
Q

Slit like central pallor

A

Stomatocyte

39
Q

Disease associated with dacryocyte

A 
PPBMM 
primary myelofibrosis 
Pernicious anemia 
Beta thalassemia 
Myelophthisic anemia 
Megaloblastic anemia
40
Q

Elongated cell with point on each end
S shaped
No central pallow

A

Sickle cell (drepanocyte)

41
Q

Composition of HB C crystal

A

Hemoglobin C

42
Q

Disease associated with mouth cell

A 
HARE 
hereditary stomatocytosis 
Acquired stomatocytosis 
Rh null syndrome 
Electrolyte imbalance
43
Q

Cigar shaped cell

A

Elliptocyte

44
Q

Egg shaped

45
Q

Disease associated with elliptocyte

A 
MITH 
Myelophthisic anemia 
Iron deficiency anemia 
Thalassemia major
Hereditary elliptocytosis
46
Q

Hexagonal structure of dense hb within the membrane

Very red

A

Hemoglobin C crystal

47
Q

Disease associated with drepanocyte

A

Sickle cell anemia

Sickle cell b-thalassemia

48
Q

Composition of sickle cell

A

Hemoglobin S

49
Q

Poikilocyte with finger like projections and may appear folded

A

Hemoglobin SC crystal

50
Q

Disease associated with hb sc crystal

A

Hemoglobin sc disease

51
Q

Dense hb protruding from the membrane

A

Hb SC crystal

52
Q

Hemoglobin sc crystal composition

A

Hemoglobin SC

53
Q

Associated disease of hb C crystal

A

Homozygous hemoglobin C disease

54
Q

What are the rbc inclusion normally stained with Wright stain?

A

Basophilic stippling, cabot rings, howell jolly bodies, pappenheimer bodies

55
Q

Rbc inclusion normally stained with supravital stain

A

Heinz bodies and hemoglobin H

56
Q

It appears fine or coarse punctate granules and contains rna and mitochondrial remnants

A

Basophilic stippling

57
Q

Associated disease with fine granules. ( basophilic)

A

Increased polychromatophilia

58
Q

Associated disease with coarse granules ( basophilic stipp)

A 
MALT 
Megaloblastic anemia 
Abnormal heme synthesis 
Lead poisoning 
Thalassemia
59
Q

Composed of DNA. State its number per cell

A

Howell jolly bodies

1-2

60
Q

Associated disease of Cabot ring

A

MM
Megaloblastic anemia
Myelophthisic anemia

61
Q

Has remnants of mitotic spindle and has an appearance of figure eight.

A

Cabot ring

62
Q

Disease associated with howell jollybodies

A 
PPHM 
Post splenectomy  
Pernicious anemia 
Hemolytic anemia 
Megaloblastic anemia
63
Q

Howell jolly bodies are remnants of what rbc stage of maturation?

A

Orthochromic erythroblast

64
Q

These are fine granules in clusters and is composed of iron

A

Pappenheimer bodies

65
Q

pappenheimer stained with iron stain is called

A

Siderotic granules

66
Q

Supravital stains

A

New methylene blue
Brillian cresyl blue
Methyl violet
Crystal violet

67
Q

Results from cell shrinkage or crenation

A

Echinocyte

68
Q

Disease associated with heinz bodies

A

GUC
G6PD def
Uneven hemoglobin
Congenital hemolytic anemia

69
Q

Disease associated with hemoglobin H

A

Hb H disease

70
Q

Disease associated with pappenheimer bodies

A 
SSMHH 
Sideroblastic anemia 
Splenectomy 
Megaloblastic anemia 
Hemolytic anemia
71
Q

Hemoglobin H composition

A

Hemoglobin beta-chains

72
Q

Heinz bodies composition

A

Denatured hemoglobin

Hema (1 decks)

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