Chapter 18 Endocrinology Flashcards
What does the Endocrine System do?
Slowly But effectively Maintaining Homeostasis
Where are the hormones released?
The Blood Stream
What are Hormones?
Chemical messengers that are transported in the bloodstream and are two alter the activities of a specific cells in other tissues.
What do all Target cells have?
Specific Receptors.
T/F Target Cells can respond to only one Hormone at a time?
False, They can respond to several at a time.
What are Water soluble Hormones including epi and nor epi classified as?
Amino Acid Derivatives ( Tyrosin)
What is Peptide Hormones composed of?
Amino Acids
What type of Hormone is Insulin?
Peptide
Sex Hormones are what?
Steroids
Charitistics of Steroid Hormones (4)
1) Lipid soluble
2) Similar structure to Cholesterol
3) Binds with intercellular receptors
4) Gene Transcription occurs when binding to receptors s
What is a called when a hormone works with a second messenger?
Catecholamine
What is the second messenger that Epi and Nor-Epi work with?
Cyclic AMP
Hormones that change, Quantities, activities, and identities are called what?
Enzymes
What does the enzyme Kinase Preform?
Phosphorylation
What do G Proteins do?
Connect first and second messengers
What do Calcium ions serve as a second messenger for?
Calmodulin
Why does Cyclic AMp act as the second messenger?
B/c it activates protein Kinases
T/F, Do Catecholamines, Peptide Hormones, and eicosanoids Need a second messenger?
True
T/F, Thyroid hormones and steroids get stopped at the cell membrane?
False
When a catecholamine or peptide hormone bind with a receptor what happens next?
The second messenger appears in the cytoplasm of the cell
What happens when the enzyme adenyl cyclase is activated
cAMP is formed, which means If the adenyl cyclase activity of the liver cells were missing, Glucagon hormones could no longer stimulate the release of insulin
When PDE (phosphodiesterase) is activated, what happens?
cAMP is broken down.
RH (Realising Hormone) and IH (Inhibiting hormone) control the functions of what?
The Anterior Pituitary Gland
Where do Rh and IH are released from where?
The Median Eminence of the Hypothalamus