Chapter 18 Flashcards
The hypothalamus produces two hormones that are stored in the posterior pituitary gland. What are they?
ADH and Oxytocin
What is the function of the hormone ADH, that is produced in the hypothalamus and stored in the posterior pituitary gland?
Promotes water retention my targeting the DCT and CD of the kidneys.
What are the functions of the hormone Oxytocin (OT) that is produced by the hypothalamus and stored in the posterior pituitary gland?
1) Induces contractions of the uterus during labor.
2) Is responsible for the “milk let-down” reflex after childbirth
The hypothalamus controls the secretion/production of hormones of the anterior pituitary glands through hormones called?
Regulatory hormones
What are the two types of regulatory hormones that the hypothalamus releases to control the secretions of the anterior pituitary glands?
1) Releasing hormones (RH)
2) Inhibiting hormones (IH)
The anterior pituitary gland contains 5 populations of cells that produce/secrete different hormones. What are these cells and hormones?
1) Somatotrophs:
- hGH
2) Corticotrophs:
- ACTH
3) Lactotrophs:
- Prolactin (PRL)
4) Thyrotrophs:
- TSH
5) Gonadotrophs:
- FSH (folical stimulating hormone)
- LH (luteinizing hormone)I
Cells called somatotrophs in the anterior pituitary gland produce the hormone hGH. What is the function of hGH?
hGH target body cells (muscle, bone, cartilage etc.) for growth, development, maintenance, and repair.
What are the three parts of the pituitary gland?
- Pars distalis (the anterior pituitary lobe)
- Pars intermedia (the middle section)
- Pars nervosa (posterior pituitary lobe)
Cells called corticotrophs that are in the anterior pituitary produce the hormone ACTH. What are the functions of ACTH?
Targets two different zones of the adrenal cortex:
1) Zona reticularis: causes the release of androgens to maintain secondary sexual characteristics in both females and males.
2) Zona Fasciculata: causes the release of cortisol (which has an anti-inflammatory effect)
Androgen is produced by both females and males, but converted into different hormones by females and males. What are they?
Testosterone in males and estrogen in females
(Side note: a hyper secretion of androgen in males and females causes the excess to be converted into the opposite one that is typically made. For instance if a male secretes an excess amount of androgen the excess will be converted into estrogen)
The cells lactotrophs that are in the anterior pituitary secrete the hormone prolactin (PRL). What are the functions of this hormone?
Prolactin is partly responsible for mammary gland development and is responsible or milk production
The cells thyrotrophs that are in the anterior pituitary produce the hormone TSH . What is the function of this hormone?
TSH stimulates follicular cells In the thyroid gland to produce T3 and T4 (which regulate metabolic rate).
The gonadotrophs that are in the anterior pituitary secrete two hormones that target the gonads. That is FSH (folical stimulating hormone) and LH (luteinizing hormone). What are the functions of these hormones?
• FSH:
- In males, tigers sustentacular cells and promotes spermatogenesis.
- In females, initiates follicle development in the ovaries.
•LH:
- In males, targets the Leydig cells and promotes secretion of testosterone.
- In females, an LH surge causes ovulation/promotes formation of the corpus luteum (which secrets progesterone).
What are the three different zones of the adrenal context from lateral to medial and what do they release?
1) Zona reticularis -» aldosterone
2) Zona fasciculata -» cortisol
3) Zona glomerulosa -» androgens
The Pars intermedia of the pituitary gland produces the hormone MSH (Melanocyte Stimulating Hormone). What is the function of this hormone?
MSH induces melanocytes to produce melanin (pigments of skin, eyes and hair).