Chapter 18 Flashcards
Endocrine system
Coordinated the function of body systems, along with the nervous system
Exocrine gland
Discharge secretions, viaduct, on to the epithelial surfaces, usually for digestion and lubrication
Endocrine gland
Discharge secretions, (hormones) into interstitial fluid, for regulation of metabolism
(The hormones then diffuse into the blood)
Hormones
Chemical messenger, produced in small amounts, transported in the blood, then interact with specific cells, to stimulate physiologic changes
Target Cell
Cell that contains specific receptor sites for a specific hormone
(Each hormone has a specific shape that matches the contour of the receptor site)
Paracrine hormone
A type of local hormone that is secreted by cell(s) then diffuse to nearby cells/tissues to stimulate physiological changes
True
Endocrine hormones (in contrast to local hormones) travel away from the site of release to stimulate other tissue
Autocrine hormone
A type of local horned that is secreted by cells, then interact with receptor on the cell that releases the hormone, to timulate physiological changes
Up regulation
When a cell increases the number of hormone receptors becoming more sensitive to stimulation
Down regulation
When a cell reduces the number of receptors, becoming less sensitive to stimulation
Synergistic effect
When two or more hormones ( or any chemical) act together to produce a greater effect than an individual hormone
Permissive effect
One hormone enhances the target cells response to a second hormone that is secreted later
Antagonistic effect
When one hormone opposes the action of another hormone
Example of lipid soluble hormones
Steroid, thyroid hormones and nitric oxide
How are hydrophobic hormones transported?
They are transported by various proteins in the blood
Example: albumins, globulins