Chapter 175 General Considerations on Bacterial Diseases

Question 1

Four phyla under which 98% of skin bacteria belong to

Answer 1

actinobacteria (corynebacteria, propionibacteria)
firmicutes (staphylococcus)
bacteroidetes
proteobacteria

Question 2

two major AMPs in the skin

amp = antimicrobial peptide

Answer 2

cathelicidin

defensin

Question 3

True or false:

TH2 cells suppress AMP production

Answer 3

true

psoriatic skin has elevated or normal AMP, hence resistant to bacterial and viral infection

Question 4

three pattern recognizing receptors (PRRs)

Answer 4

antimicrobial peptide
toll like receptors
complement system

Question 5

TLR that recognizes peptidoglycan of gram positive bacteria

Answer 5

TLR 2

Question 6

TLR that recognizes lipopolysaccharide of gram negative bacteria

Answer 6

TLR 4

Question 7

TLR that recognizes peptidoglycan of flagella

Answer 7

TLR 5

Question 8

componentn of staph aureus that inactivates defensin

Answer 8

staphylokinase

Question 9

componentn of staph aureus that inactivates cathelicidin

Answer 9

aureolysin A