Chapter 17 Flashcards
Olfaction
Sense of smell.
Olfactory epithelium
Where the receptors for olfaction are located. Occupies the superior part of the nasal cavity, covering the inferior surface of the cribriform plate and extending along the superior nasal concha.
What three kinds of cells does the olfactory epithelium consist of?
- Olfactory receptor cells
- Supporting cells
- Basal cells
Olfactory receptor cells
Are the first-order neurons of the olfactory pathway. Are bipolar neurons with an exposed, knob-shaped dendrite and an axon projecting through the cribriform plate that ends in the olfactory bulb.
Olfactory cilia
Extend from the dendrites of olfactory receptors. Sites of olfactory transduction.
Olfactory receptor
Proteins that detect inhaled chemicals.
Odorants
Chemicals that bind to and stimulate the olfactory receptors in the olfactory cilia.
Supporting cells (of the olfactory epithelium)
Columnar epithelial cells of the mucous membrane that line the nose. They provide physical support, nourishment, and electrical insulation for the olfactory receptor cells and help detoxify chemicals that come in contact with the olfactory epithelium.
Basal cells (of the olfactory epithelium)
Stem cells located between the bases of the supporting cells. They continually undergo cell division to produce new olfactory receptor cells, which live for only about two months before being replaced.
Olfactory glands
AKA Bowman’s glands; produce mucus that is carried to the surface of the epithelium by ducts. The secretion moistens the surface of the olfactory epithelium and dissolves odorants so that transduction can occur.
Olfactory transduction
Binding of an odorant molecule to an olfactory receptor protein activates a G protein and adenylyl cyclase, resulting in the production of cyclic AMP (cAMP). Cyclic AMP (cAMP) opens cation channels, and Na+ and Ca2+ ions enter the olfactory receptor cell. The resulting depolarization may generate an action potential, which propagates along the axon of the olfactory receptor cell.
Adaptation
Decreasing sensitivity.
Gustation
Sense of taste. Is a chemical sense.
What are the five primary tastes? And how are each of the tastes produced?
- Salty: is caused by the presence of sodium ions (Na+) in food.
- Sour: is produced by hydrogen ions (H+) released from acids.
- Sweet: is elicited by sugars such as glucose, fructose, and sucrose and by artificial sweeteners such as saccharin, aspartame, and sucralose.
- Bitter: is caused by a wide variety of substances, including caffeine, morphine, and quinine. In addition, many poisonous substances like strychnine have a bitter taste.
- Umami: described as “meaty” or “savory.” Is elicited by amino acids (especially glutamate) that are present in food.
Taste bud
Where the receptors for taste are located. Most are found on the tongue, and some are found on the soft palate, pharynx, and epiglottis.
What three kinds of epithelial cells make up taste buds?
- Supporting cells
- Gustatory cells
- Basal cells
Supporting cells (of the taste buds)
Surround about 50 gustatory receptor cells in each taste bud.
Gustatory receptor cells
At their base they synapse with dendrites of the first-order neurons that form the first part of the gustatory pathway. The dendrites of each first-order neuron branch profusely and contact many gustatory receptor cells in several taste buds. Has a life span of about 10 days.
Gustatory microvilli
AKA gustatory hairs; project from each gustatory receptor cell to the external surface through the taste pore, an opening in the taste bud. Sites of taste transduction.
Basal cells (of the taste buds)
Stem cells that are found at the periphery of the taste bud near the connective tissue layer. Produce supporting cells, which then develop into gustatory receptor cells.
Papillae
AKA papilla; elevations of the tongue where taste buds are found. Increase the surface area and provide a rough texture to the upper surface of the tongue.
What are the three types of papillae that contain taste buds?
- Vallate papillae
- Fungiform papillae
- Foliate papillae
Vallate papillae
AKA circumvallate papillae; about 12 very large, circular elevations that form an inverted V-shaped row at the back of the tongue. Each of these papillae houses 100–300 taste buds.
Fungiform papillae
Mushroom-shaped elevations scattered over the entire surface of the tongue that contain about five taste buds each.
Foliate papillae
Are located in small trenches on the lateral margins of the tongue, but most of their taste buds degenerate in early childhood.
Filiform papillae
Pointed, threadlike structures that contain tactile receptors but no taste buds. They increase friction between the tongue and food, making it easier for the tongue to move food in the oral cavity. Are found on the entire surface of the tongue.
Tastants
Chemicals that stimulate gustatory receptor cells.
The receptor potential arises ______ for different tastants.
Differently
The ______ ions in a salty food enter gustatory receptor cells via __ channels in the plasma membrane. The accumulation of __ inside the cell causes ______, which leads to release of neurotransmitter. The hydrogen ions (H+) in sour tastants flow into gustatory receptor cells via H+ channels. Again, the result is depolarization and the liberation of neurotransmitter. Other tastants, responsible for stimulating sweet, bitter, and umami tastes, do not themselves enter gustatory receptor cells. Rather, they bind to receptors on the plasma membrane that are linked to G proteins. The G proteins then activate enzymes that produce the second messenger inositol trisphosphate (IP3). IP3 in turn ultimately causes depolarization of the gustatory receptor cell and release of neurotransmitter.
Sodium; Na+; Na+; depolarization
Why is vision important?
Vision is extremely important to human survival because it allows us to view potentially dangerous objects in our surroundings. More than half the sensory receptors in the human body are located in the eyes, and a large part of the cerebral cortex is devoted to processing visual information.
Visible light
The part of the electromagnetic spectrum with wavelengths ranging from about 400 to 700 nm. Visible light exhibits colors: The color of visible light depends on its wavelength (Eg. Light that has a wavelength of 400 nm is violet, and light that has a wavelength of 700 nm is red). An object can absorb certain wavelengths of visible light and reflect others; the object will appear the color of the wavelength that is reflected (Eg. A green apple appears green because it reflects mostly green light and absorbs most other wavelengths of visible light). An object appears white because it reflects all wavelengths of visible light. An object appears black because it absorbs all wavelengths of visible light.
What are the five accessory structures of the eye?
- Eyelids
- Eyelashes
- Eyebrows
- Lacrimal (tear-producing) apparatus
- Extrinsic eye muscles
Eyelids
AKA palpebrae (or palpebra); shade the eyes during sleep, protect the eyes from excessive light and foreign objects, and spread lubricating secretions over the eyeballs. The upper eyelid is more movable than the lower eyelid.
Levator palpebrae superioris muscle
In the superior region of the upper eyelid.
Palpebral fissure
The space between the upper and lower eyelids that exposes the eyeball.
Lateral commissure
Angles of the palpebral fissure. Narrower and closer to the temporal bone.
Medial commissure
Angles of the palpebral fissure. Broader and nearer the nasal bone.
Lacrimal caruncle
A small, reddish elevation in the medial commissure. Contains sebaceous (oil) glands and sudoriferous (sweat) glands.
From superficial to deep, what seven things does each eyelid consist of?
- Epidermis
- Dermis
- Subcutaneous tissue
- Fibers of the orbicularis oculi muscle
- Tarsal plate
- Tarsal glands
- Conjunctiva
Tarsal plate
A thick fold of connective tissue that gives form and support to the eyelids.
Tarsal glands
AKA Meibomian glands; a row of elongated modified sebaceous glands embedded in each tarsal plate. Secrete a fluid that helps keep the eyelids from adhering to each other.
Conjunctiva
A thin, protective mucous membrane composed of nonkeratinized stratified squamous epithelium with numerous goblet cells that is supported by areolar connective tissue.
Palpebral conjunctiva
Lines the inner aspect of the eyelids.
Bulbar conjunctiva
Passes from the eyelids onto the surface of the eyeball, where it covers the sclera but not the cornea. Over the sclera, the conjunctiva is vascular. Dilation and congestion of the blood vessels of the bulbar conjunctiva due to local irritation or infection are the cause of bloodshot eyes.
Eyelashes
Project from the border of each eyelid.
Eyebrows
Arch transversely above the upper eyelids, and help protect the eyeballs from foreign objects, perspiration, and the direct rays of the sun.
Sebaceous ciliary glands
Sebaceous glands at the base of the hair follicles of the eyelashes. Release lubricating fluid into the follicles. Infection of these glands, usually by bacteria, causes a sty.
Lacrimal apparatus
Is a group of structures that produces and drains lacrimal fluid or tears in a process called lacrimation.
______ secrete tears into the ______, which distribute tears over surface of the eyeball. ______ drain tears into the ______, which drains tears into the ______, which drains tears into the nasal cavity.
Lacriminal glands; excretory lacrimal ducts; superior or inferior lacrimal canaliculi; lacrimal sac; nosalacriminal duct
Lacrimal puncta
Two small openings.
Lacrimal fluid
Produced by lacrimal glands. Is a watery solution containing salts, some mucus, and lysozyme (a protective bactericidal enzyme). This fluid protects, cleans, lubricates, and moistens the eyeball. Spread medially over the surface of the eyeball by the blinking of the eyelids. Each gland produces about 1mL of lacrimal fluid per day.
Extrinsic eye muscles
Extend from the walls of the bony orbit to the sclera of the eye and are surrounded in the orbit by a significant quantity of periorbital fat. These muscles are capable of moving the eye in almost any direction.
__ extrinsic eye muscles move each eye.
6
Eyeball
Measures about 2.5 cm (1 in.) in diameter. Anterior one-sixth is exposed – the remainder is recessed and protected by the orbit, into which it fits.
What three layers does the wall of the eyeball consist of?
- Fibrous tunic
- Vascular tunic
- Retina (inner tunic)
Fibrous tunic
The superficial layer of the eyeball.
What two structures does the fibrous tunic consist of?
- Cornea
- Sclera
Cornea
Admits and refracts (bends) light.
Sclera
Provides shape and protects inner parts.
Scleral venous sinus
AKA canal of Schlemm; an opening at the junction of the sclera and cornea, which aquous humor drains into.
Vascular tunic
AKA uvea; the middle layer of the eyeball.
What three structures does the vascular tunic consist of?
- Choroid
- Ciliary body
- Iris
Choroid
Provides blood supply and absorbs scattered light.
Ciliary body
Secretes aqueous humour and alters shape of lens for near or far vision (accommodation).
Ora serrata
The jagged anterior margin of the retina.
Ciliary processes
Protrusions or folds on the internal surface of the ciliary body. They contain blood capillaries that secrete aqueous humor.
Zonular fibers
AKA suspensory ligaments; extend from the ciliary process and attach to the lens. Consist of thin, hollow fibrils that resemble elastic connective tissue fibers.
Ciliary muscle
A circular band of smooth muscle. Contraction or relaxation of the ciliary muscle changes the tightness of the zonular fibers, which alters the shape of the lens, adapting it for near or far vision.
Iris
Regulates amount of light that enters eyeball.
Pupil
The hole in the center of the iris. Regulates the amount of light entering the eyeball.
Circular muscles
AKA sphincter pupillae; contract to decrease the size of the pupil (constrict the pupil).
Radial muscles
AKA dilator muscles: contract to increase the size of the pupil (dilate the pupil).