Chapter 16-Innate Immunity:Nonspecific Defenses Of Host Flashcards
Susceptibility:
Lack of resistance to disease
4 Nonspecific defenses of the host?
- susceptibility
- immunity
- innate immunity
- adaptive immunity
Immunity:
Ability to ward off disease
Innate immunity:
Nonspecific immunity defenses that protect against any pathogen
Adaptive immunity:
Specific immunity block or isolate from letting specific pathogen in.
First line of defense examples:
- intact skin
- mucous membranes
- normal microbiota
Second line of defense:
- natural killer cells and phagocytic white blood cells
- inflammation
- fever
- antimicrobial substance
Third line of defense:
- specialized lymphocytes: T & B cells
- antibodies
First line defense- 8 mechanical factors?
- intact skin
- mucous membranes
- lacrimal apparatus
- saliva
- ciliary escalator
- epiglottis
- urine
- vaginal secretions
Intact skin:
Epidermis consists of tightly packed cells with many layers, keratin top layer, dryness, shedding.
Mucous membranes:
Contain mucous to trap particles
Lacrimal apparatus:
Produces continued washing that removes pathogens
Saliva:
Produced by salivary glands
Ciliary escalator:
Produces mucous.
Microbes are trapped in the mucous and are transported away from the lungs.
Epiglottis:
Covers larynx to keep microbes out of the lower respiratory