Chapter 16: Drug Therapy to Increase Pain, Fever and Inflammation

Question 1

Antiprostaglandin

Answer 1

drug that inhibits the synthesis of prostaglandins

Question 2

antipyretic

Answer 2

drug that has the ability to lower body temperature

Question 3

Arachidonic Acid

Answer 3

phospholipid released in the cell membrane in response to cellular injury.

Question 4

Cyclooxygenase

Answer 4

enzyme that produces prostaglandins from arachidonic acids

Question 5

hyperuricemia

Answer 5

elevated levels of uric acid in the blood resulting form accelerated generation of uric acid through purine metabolism or impaired renal excretion of uric acid

Question 6

Nonsteroidal anti-inflammatory drug (NSAID)

Answer 6

medication that inhibits the synthesis of prostaglandins; used to prevent and treat mild to moderate pain and inflammation

Question 7

prostaglandin

Answer 7

chemical mediator found in most body tissues; helps regulate many cell functions and participate in the inflammatory response as well as initiate uterine contractions in labor

Question 8

pyrogen

Answer 8

fever-producing agents

Question 9

Reye’s Syndrome

Answer 9

potentially fatal disease characterized by encephalopathy and fatty liver accumulations; associated with the use of aspirin and NSAIDs after viral infections such as chicken pox or influenza in children and adolescents

Question 10

salicylism

Answer 10

toxic effects of a salicylate drug; may occur with an acute overdose or with chronic use of therapeutic doses, especially the higher doses taken for anti-inflammatory effects

Question 11

Tophi

Answer 11

deposits of uric acid crystals in the joints, kidneys, and soft tissues

Question 12

uricosuric

Answer 12

drug that increases urinary excretion of uric acid