chapter 16 biology Flashcards

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1
Q

how many DNA binding motifs are there

A

three

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2
Q

identify when gene expression is usually controlled

A

during transcription initiation

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3
Q

describe the usual action of regulatory proteins

A

they bind to DNA and they can block or stimulate transcription and modulate binding of RNA polymerase to promoter

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4
Q

control of gene expression in prokaryotes

A

Regulate gene expression in response to the environment

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5
Q

control of gene expression in eukaryotes

A

regulate gene expression to maintain homeostasis

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6
Q

explain how proteins can interact with base pairs WITHOUT unwinding the DNA helix

A

the bae pairs have unique accessibility patterns allowing the proteins to bind at the major groove

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7
Q

control of gene expression using repression

A

it is capable of making an enzyme but does not

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8
Q

control of gene expression using induction

A

enzymes for certain pathways are produced in response to substrate

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9
Q

explain the control of gene expression in the lac operon

A

uses a lac repressor to suppress lactose that blocks transcription to operon and CAP as a glucose sensor activating transcription to operon when glucose is low

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10
Q

what is the main energy source for lac operon

A

lactose

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11
Q

what does lac operon use to sense lactose

A

allolactose

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12
Q

what is the role of ubiquitin in the degradation of proteins

A

marks proteins for destruction at proteasome

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12
Q

explain control of gene expression in the trp operon

A

uses trp repressor in a helix turn helix that bind to operator site located adjacent to trp promoter

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13
Q

what is the job of the trp operon

A

biosynthesis of tryptophan

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14
Q

what does the trp operator site require

A

corepressor

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15
Q

what are the roles of general transcription factors

A

initiate transcription by forming the initiation complex

16
Q

what are the roles of specific transcription factors

A

act in the tissue for time dependent matters to stimulate higher levels of transcription

17
Q

how can transcription factors have an effect from a distance in DNA

A

they bend DNA to form a loop to position the enhancer closer to the promotor

18
Q

what are 2 types of epigenetic mark

A

dna methylation and x chromosome modification

19
Q

what happens with dna methylation

A

high levels correlate with inactive genes

20
Q

what happens with x chromosome modification

A

female mammals inactivate 1 X chromosome

21
Q

how do small RNAs effect gene expression

A

after transcription they protect genome RNA silencing pathways implicated in formation of heterochromatin in different organisms