chapter 16 Flashcards

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1
Q

who conducted the x ray diffraction studies that were key to the discovery of the structure of DNA?

A

franklin

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2
Q

DNA replication is said to be semiconservatice, which of the following statements correctly explains what this means.

A

each new double helix consists of one old and one new strand.

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3
Q

what are the repetitive DNA sequences present at the ends of eukaryotic chromosomes called?

A

telomeres

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4
Q

what process repairs damage to a preexisting double helix?

A

nucleotide excision repair

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5
Q

what are chromosomes made of

A

DNA and protein

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6
Q

which of the following is true of DNA during interphase?

A

it exists as chromatin and is less condensed than mitotic chromosomes.

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7
Q

when thomas hunt morgan crossed red eyed F1 generation flies to each other, the F2 generation included both red and white eyed flies, but all the white eyed flies were male, which of these best explains morgans results

A

the gene involved is located on the X chromosome

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8
Q

which of the following statements correctly describes the chromosome theory of inheritance as it was understood in the early 20th century.

A

mendelian genes are at a specific loci on the chromosome, and in turn, segregate during meiosis

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9
Q

frederick griffith heat killed a culture of pathogenic bacteria. he split up the sample and injected half of it into mice. The mice lived. He then mixed the other half with a living, non pathogenic bacteria strain and injected the mixture into mice. The mice died. These results best support which of the following conclusions.

A

a substance had been transferred from pathogenic to nonpathogenic bacteria,

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10
Q

Frederick Griffith heat-killed a culture of pathogenic bacteria. He split the sample and injected half of it into mice. The mice lived. He then mixed the other half of the sample with a living, nonpathogenic bacteria strain and injected the mixture into mice. The mice died. Which of the following describes a treatment that would help clarify interpretation of these data?

A

examining tissue from the dead mice (injected with mixed sample) for the presence of pathogenic bacteria.

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11
Q

which of the following characteristics allowed Hershey and Chase to determine whether the genetic material was made of DNA or protein?

A

DNA contains phosphoro0us, whereas protein does not.

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12
Q

which of the following investigators was responsible for determining that DNA contains equal amounts of adenine and thymine, and equal amounts of guanine and cytosine.

A

erwin chargaff

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13
Q

which of the following combinations of base pairs will be found in a molecule of DNA.

A

A + C = G + T

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14
Q

Two students decided to repeat the Hershey and Chase experiment, with modifications. Like Hershey and Chase they used radioactive sulfur but they substituted radioactive nitrogen for radioactive phosphate. They reasoned that each nucleotide has only one phosphate and two to five nitrogen atoms. Thus, labeling the nitrogen atoms would provide a stronger signal than labeling the phosphates. Which of the following is the biggest shortcoming in their experimental design?

A

The radioactivity would not distinguish between DNA and proteins because proteins contain nitrogen.

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15
Q

which of the following statements accurately describes difference between DNA replication in prokaryotes and DNA replication in eukaryotes.

A

prokaryotic chromosomes have a single origin of replication, whereas eukaryotic chromosomes have many.

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16
Q

DNA strands are antiparallel, which of the following statements defines antiparallel.

A

A 5’ to #’ DNA strand is paired with the 3’ to 5’ DNA strand.

17
Q

In E. coli, a mutation in a gene is called dnaB, it prevents the helicase rom binding at the origin o replication, which of the following events would you expect to occur as a result of this mutation.

A

no replication fork will be formed.

18
Q

radioactive thymine is added to media containing one actively dividing E. coli bacterium. Which of the following outcomes would e seen after a single cell division.

A

DNA in both daughter cells would be radioactive.

19
Q

which list provides the correct enzyme order required for nucleotide excision repair of a thymine dimer

A

nuclease, DNA polymerase, DNA ligase.

20
Q

which of the following is a reason that the low error rate of DNA replication is important to evolution

A

rare errors are the source of variation.

21
Q

in bacteria, what is the function of DNA polymerase III

A

to add nucleotides the 3’ end of a growing DNA strand.

22
Q

which of the following statements correctly describes the difference between ATP used in metabolism an the nucleotides used as a building block during DNA synthesis.

A

the nucleotides have the sugar deoxyribose; ATP has the sugar ribose.

23
Q

which of the following statements correctly describes the difference between the leading and the lagging strands of DNA in DNA replications.

A

the leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction.

24
Q

which of the following is a reason that a new DNA strand elongates only in the 5’ to 3’ direction during DNA replication?

A

dehydration reactions require a free -OH group.